Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns
The initial colonization of the intestine represents one of the most profound immunological exposures faced by the newborn. During the first three years of life, the intestinal microbial composition undergoes significant changes. At birth, the digestive tract is rapidly colonized by microorganisms o...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Data in Brief |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S235234092400101X |
| _version_ | 1797256343829086208 |
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| author | Kenza Hattoufi Fatiha Raji Houssain Tligui Jaafar Heikel Hassan Aguenaou Amina Barkat |
| author_facet | Kenza Hattoufi Fatiha Raji Houssain Tligui Jaafar Heikel Hassan Aguenaou Amina Barkat |
| author_sort | Kenza Hattoufi |
| collection | DOAJ |
| description | The initial colonization of the intestine represents one of the most profound immunological exposures faced by the newborn. During the first three years of life, the intestinal microbial composition undergoes significant changes. At birth, the digestive tract is rapidly colonized by microorganisms of maternal and environmental origins. Microbiota's composition is influenced by various factors, including the mode of delivery, gestational age, type of feeding, and medication use. Through the current study, we specifically focused on elucidating the dynamics of gut microbiota colonization within the first three weeks of life of infants, shedding light on this critical phase of development.A prospective cohort study involving 29 preterm infants was conducted from January to September 2021 at the National Reference Center for Neonatology and Nutrition, in collaboration with the research laboratory of Children's Hospital at the University Hospital Center Ibn Sina in Rabat. Stool samples were collected from each infant's diapers into a sterile tube and send for laboratory analysis.A total of 203 stool samples were collected. For each newborn, one stool sample was obtained within the first 48 h after birth, followed by two samples per week over a period of three weeks. The microbial compositions of these samples were analyzed using real-time polymerase chain reaction. |
| first_indexed | 2024-03-08T00:48:55Z |
| format | Article |
| id | doaj.art-549078ab03754a0aa0cc4a3078af396e |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-04-24T22:20:15Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-549078ab03754a0aa0cc4a3078af396e2024-03-20T06:09:48ZengElsevierData in Brief2352-34092024-04-0153110129Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newbornsKenza Hattoufi0Fatiha Raji1Houssain Tligui2Jaafar Heikel3Hassan Aguenaou4Amina Barkat5National Reference Center in Neonatology and Nutrition, Children's Hospital, Ibn Sina University Hospital Centre, Rabat, Morocco; Research Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, Morocco; Corresponding author.Joint Research Unit in Nutrition and Food, RDC-Nutrition AFRA/IAEA, Ibn Tofail University-CNESTEN, MoroccoResearch Laboratory of Ibn Sina University Hospital, Rabat, Morocco; Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoMohammed VI University of Health Sciences, Casablanca, MoroccoJoint Research Unit in Nutrition and Food, RDC-Nutrition AFRA/IAEA, Ibn Tofail University-CNESTEN, MoroccoNational Reference Center in Neonatology and Nutrition, Children's Hospital, Ibn Sina University Hospital Centre, Rabat, Morocco; Research Team on Health and Nutrition of Mother and Child, Faculty of Medicine and Pharmacy, Mohammed V University in Rabat, MoroccoThe initial colonization of the intestine represents one of the most profound immunological exposures faced by the newborn. During the first three years of life, the intestinal microbial composition undergoes significant changes. At birth, the digestive tract is rapidly colonized by microorganisms of maternal and environmental origins. Microbiota's composition is influenced by various factors, including the mode of delivery, gestational age, type of feeding, and medication use. Through the current study, we specifically focused on elucidating the dynamics of gut microbiota colonization within the first three weeks of life of infants, shedding light on this critical phase of development.A prospective cohort study involving 29 preterm infants was conducted from January to September 2021 at the National Reference Center for Neonatology and Nutrition, in collaboration with the research laboratory of Children's Hospital at the University Hospital Center Ibn Sina in Rabat. Stool samples were collected from each infant's diapers into a sterile tube and send for laboratory analysis.A total of 203 stool samples were collected. For each newborn, one stool sample was obtained within the first 48 h after birth, followed by two samples per week over a period of three weeks. The microbial compositions of these samples were analyzed using real-time polymerase chain reaction.http://www.sciencedirect.com/science/article/pii/S235234092400101XGut MicrobiotaPrematurityTaqmanSyber GreenMorocco |
| spellingShingle | Kenza Hattoufi Fatiha Raji Houssain Tligui Jaafar Heikel Hassan Aguenaou Amina Barkat Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns Data in Brief Gut Microbiota Prematurity Taqman Syber Green Morocco |
| title | Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns |
| title_full | Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns |
| title_fullStr | Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns |
| title_full_unstemmed | Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns |
| title_short | Dataset of establishment of gut microbiota: Molecular analysis of a cohort of 29 preterm Moroccan newborns |
| title_sort | dataset of establishment of gut microbiota molecular analysis of a cohort of 29 preterm moroccan newborns |
| topic | Gut Microbiota Prematurity Taqman Syber Green Morocco |
| url | http://www.sciencedirect.com/science/article/pii/S235234092400101X |
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