Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol
Daisuke Anegawa et al. investigated the mechanisms responsible for cold resistance in the Syrian hamster’s hepatocytes, which exhibited remarkable resistance to prolonged cold culture. Their results suggest that hepatocytes exhibit diet-dependent resistance to cold, which is linked to the retention...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02297-6 |
| _version_ | 1828972365482033152 |
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| author | Daisuke Anegawa Yuki Sugiura Yuta Matsuoka Masamitsu Sone Mototada Shichiri Reo Otsuka Noriko Ishida Ken-ichi Yamada Makoto Suematsu Masayuki Miura Yoshifumi Yamaguchi |
| author_facet | Daisuke Anegawa Yuki Sugiura Yuta Matsuoka Masamitsu Sone Mototada Shichiri Reo Otsuka Noriko Ishida Ken-ichi Yamada Makoto Suematsu Masayuki Miura Yoshifumi Yamaguchi |
| author_sort | Daisuke Anegawa |
| collection | DOAJ |
| description | Daisuke Anegawa et al. investigated the mechanisms responsible for cold resistance in the Syrian hamster’s hepatocytes, which exhibited remarkable resistance to prolonged cold culture. Their results suggest that hepatocytes exhibit diet-dependent resistance to cold, which is linked to the retention of α-tocopherol in the liver. |
| first_indexed | 2024-12-14T13:26:30Z |
| format | Article |
| id | doaj.art-5490d4cebb014a8388a70e5323d72017 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-14T13:26:30Z |
| publishDate | 2021-06-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-5490d4cebb014a8388a70e5323d720172022-12-21T22:59:49ZengNature PortfolioCommunications Biology2399-36422021-06-014111110.1038/s42003-021-02297-6Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherolDaisuke Anegawa0Yuki Sugiura1Yuta Matsuoka2Masamitsu Sone3Mototada Shichiri4Reo Otsuka5Noriko Ishida6Ken-ichi Yamada7Makoto Suematsu8Masayuki Miura9Yoshifumi Yamaguchi10Hibernation Metabolism, Physiology and Development Group, Institute of Low Temperature Science, Hokkaido UniversityDepartment of Biochemistry, Keio University School of MedicinePhysical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu UniversityHibernation Metabolism, Physiology and Development Group, Institute of Low Temperature Science, Hokkaido UniversityBiomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)Hibernation Metabolism, Physiology and Development Group, Institute of Low Temperature Science, Hokkaido UniversityBiomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST)Physical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu UniversityDepartment of Biochemistry, Keio University School of MedicineDepartment of Genetics, Graduate School of Pharmaceutical Sciences, The University of TokyoHibernation Metabolism, Physiology and Development Group, Institute of Low Temperature Science, Hokkaido UniversityDaisuke Anegawa et al. investigated the mechanisms responsible for cold resistance in the Syrian hamster’s hepatocytes, which exhibited remarkable resistance to prolonged cold culture. Their results suggest that hepatocytes exhibit diet-dependent resistance to cold, which is linked to the retention of α-tocopherol in the liver.https://doi.org/10.1038/s42003-021-02297-6 |
| spellingShingle | Daisuke Anegawa Yuki Sugiura Yuta Matsuoka Masamitsu Sone Mototada Shichiri Reo Otsuka Noriko Ishida Ken-ichi Yamada Makoto Suematsu Masayuki Miura Yoshifumi Yamaguchi Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol Communications Biology |
| title | Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol |
| title_full | Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol |
| title_fullStr | Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol |
| title_full_unstemmed | Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol |
| title_short | Hepatic resistance to cold ferroptosis in a mammalian hibernator Syrian hamster depends on effective storage of diet-derived α-tocopherol |
| title_sort | hepatic resistance to cold ferroptosis in a mammalian hibernator syrian hamster depends on effective storage of diet derived α tocopherol |
| url | https://doi.org/10.1038/s42003-021-02297-6 |
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