Application of a Semi-automatic Algorithm for Identification of Molecular Components in SBML Models

Reactions forming a pathway can be rewritten by making explicit the different molecular components involved in them. A molecular component represents a biological entity (e.g. a protein) in all its states (free, bound, degraded, etc.). In this paper we show the application of a component identificat...

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Bibliographic Details
Main Authors: Giovanni Pardini, Andrea Maggiolo-Schettini, Paolo Milazzo
Format: Article
Language:English
Published: Open Publishing Association 2013-09-01
Series:Electronic Proceedings in Theoretical Computer Science
Online Access:http://arxiv.org/pdf/1309.7689v1
Description
Summary:Reactions forming a pathway can be rewritten by making explicit the different molecular components involved in them. A molecular component represents a biological entity (e.g. a protein) in all its states (free, bound, degraded, etc.). In this paper we show the application of a component identification algorithm to a number of real-world models to experimentally validate the approach. Components identification allows subpathways to be computed to better understand the pathway functioning.
ISSN:2075-2180