Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft
Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membran...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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Series: | Saudi Journal of Kidney Diseases and Transplantation |
Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=381;epage=385;aulast=Tewari |
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author | Rohit Tewari Kusum Joshi Ashwani Kumar C S Rayat Rajaram Iyer Vinay Sakhuja Mukut Minz |
author_facet | Rohit Tewari Kusum Joshi Ashwani Kumar C S Rayat Rajaram Iyer Vinay Sakhuja Mukut Minz |
author_sort | Rohit Tewari |
collection | DOAJ |
description | Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membranoproliferative glomerulonephritis with kappa light chain restriction and only one sub-class of IgG. He subsequently underwent renal transplant. Two months later, he developed acute graft dysfunction. Renal biopsy showed a recurrence of the disease. Work up for multiple myeloma was positive. Membranoproliferative pattern of injury in the posttransplant setting has a wide range of differential diagnosis, PGNMID being one of them. |
first_indexed | 2024-12-11T20:19:46Z |
format | Article |
id | doaj.art-5495e5daca6748a5a11e1fc8e118845e |
institution | Directory Open Access Journal |
issn | 1319-2442 |
language | English |
last_indexed | 2024-12-11T20:19:46Z |
publishDate | 2016-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Saudi Journal of Kidney Diseases and Transplantation |
spelling | doaj.art-5495e5daca6748a5a11e1fc8e118845e2022-12-22T00:52:06ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422016-01-0127238138510.4103/1319-2442.178568Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograftRohit TewariKusum JoshiAshwani KumarC S RayatRajaram IyerVinay SakhujaMukut MinzProliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMIDs) is a clinico-pathologic entity, the recurrence of which in the renal allograft has only recently been described. A 55-year-old male presented with rapid deterioration of renal function. Light microscopy showed membranoproliferative glomerulonephritis with kappa light chain restriction and only one sub-class of IgG. He subsequently underwent renal transplant. Two months later, he developed acute graft dysfunction. Renal biopsy showed a recurrence of the disease. Work up for multiple myeloma was positive. Membranoproliferative pattern of injury in the posttransplant setting has a wide range of differential diagnosis, PGNMID being one of them.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=381;epage=385;aulast=Tewari |
spellingShingle | Rohit Tewari Kusum Joshi Ashwani Kumar C S Rayat Rajaram Iyer Vinay Sakhuja Mukut Minz Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft Saudi Journal of Kidney Diseases and Transplantation |
title | Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
title_full | Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
title_fullStr | Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
title_full_unstemmed | Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
title_short | Early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
title_sort | early recurrence of proliferative glomerulonephritis with monoclonal immunoglobulin deposits in a renal allograft |
url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=2;spage=381;epage=385;aulast=Tewari |
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