Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review

Potential diabetic cardiomyopathy therapies targeting pyroptosis: A mini review

Pyroptosis is primarily considered a pro-inflammatory class of caspase-1- and gasdermin D (GSDMD)-dependent programmed cell death. Inflammasome activation promotes the maturation and release of interleukin (IL)-1β and IL-18, cleavage of GSDMD, and development of pyroptosis. Recent studies have repor...

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Bibliographic Details
Main Authors: Yu Jia, Dongze Li, Jing Yu, Wenli Jiang, Xiaoyang Liao, Qian Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
diabetic cardiomyopathy
pyroptosis
NLRP3
caspase-1
pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.985020/full

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