Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak.

Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak.

The most feared complication following intestinal resection is anastomotic leakage. In high risk areas (esophagus/rectum) where neoadjuvant chemoradiation is used, the incidence of anastomotic leaks remains unacceptably high (≈ 10%) even when performed by specialist surgeons in high volume centers....

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Bibliographic Details
Main Authors: Andrea D Olivas, Benjamin D Shogan, Vesta Valuckaite, Alexander Zaborin, Natalya Belogortseva, Mark Musch, Folker Meyer, William L Trimble, Gary An, Jack Gilbert, Olga Zaborina, John C Alverdy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3432121?pdf=render

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