Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor

Screening and treatment of abnormal vaginal flora during pregnancy to prevent preterm labor is a matter of debate for practicing obstetrician and physician in a country where maternal health and its outcome is a big concern. The recent evidence suggests that infection may be implicated in a substant...

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Main Authors: Gunjan Kumari, Anjali Tempe
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:MAMC Journal of Medical Sciences
Subjects:
Online Access:http://www.mamcjms.in/article.asp?issn=2394-7438;year=2015;volume=1;issue=2;spage=64;epage=68;aulast=Kumari
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author Gunjan Kumari
Anjali Tempe
author_facet Gunjan Kumari
Anjali Tempe
author_sort Gunjan Kumari
collection DOAJ
description Screening and treatment of abnormal vaginal flora during pregnancy to prevent preterm labor is a matter of debate for practicing obstetrician and physician in a country where maternal health and its outcome is a big concern. The recent evidence suggests that infection may be implicated in a substantial proportion of cases of preterm delivery. Neonatal morbidity and mortality are primarily influenced by gestational age and less so by birth weight. Microbial flora normally present in the human vagina play a key role in preventing pathological organisms including those responsible for sexually transmitted diseases, yeast infections, bacterial vaginosis (BV), and urinary tract infection. The outcome gathered from various recent studies have been remarkably consistent and managed to support the hypothesis that antibiotic treatment before 20 weeks of gestation reduces the risk of preterm birth. It is concluded that screening for abnormal vaginal flora cannot be generalized, but it may be safely carried out in pregnant women who have a previous history of preterm labor. Antibiotics with lactobacillus treatment can eradicate abnormal vaginal flora in pregnancy, however, screening and treating all pregnant women with asymptomatic BV to prevent preterm birth and its consequences is not substantiated by evidence.
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spelling doaj.art-54a07b6b22b144ef902ca83618ecbe862022-12-22T02:18:44ZengWolters Kluwer Medknow PublicationsMAMC Journal of Medical Sciences2394-74382015-01-0112646810.4103/2394-7438.157912Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm LaborGunjan KumariAnjali TempeScreening and treatment of abnormal vaginal flora during pregnancy to prevent preterm labor is a matter of debate for practicing obstetrician and physician in a country where maternal health and its outcome is a big concern. The recent evidence suggests that infection may be implicated in a substantial proportion of cases of preterm delivery. Neonatal morbidity and mortality are primarily influenced by gestational age and less so by birth weight. Microbial flora normally present in the human vagina play a key role in preventing pathological organisms including those responsible for sexually transmitted diseases, yeast infections, bacterial vaginosis (BV), and urinary tract infection. The outcome gathered from various recent studies have been remarkably consistent and managed to support the hypothesis that antibiotic treatment before 20 weeks of gestation reduces the risk of preterm birth. It is concluded that screening for abnormal vaginal flora cannot be generalized, but it may be safely carried out in pregnant women who have a previous history of preterm labor. Antibiotics with lactobacillus treatment can eradicate abnormal vaginal flora in pregnancy, however, screening and treating all pregnant women with asymptomatic BV to prevent preterm birth and its consequences is not substantiated by evidence.http://www.mamcjms.in/article.asp?issn=2394-7438;year=2015;volume=1;issue=2;spage=64;epage=68;aulast=KumariAerobic vaginitisbacterial vaginosisvaginal flora
spellingShingle Gunjan Kumari
Anjali Tempe
Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
MAMC Journal of Medical Sciences
Aerobic vaginitis
bacterial vaginosis
vaginal flora
title Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
title_full Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
title_fullStr Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
title_full_unstemmed Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
title_short Should Abnormal Vaginal Flora in 2 nd Trimester of Pregnancy be Treated to Prevent Preterm Labor
title_sort should abnormal vaginal flora in 2 nd trimester of pregnancy be treated to prevent preterm labor
topic Aerobic vaginitis
bacterial vaginosis
vaginal flora
url http://www.mamcjms.in/article.asp?issn=2394-7438;year=2015;volume=1;issue=2;spage=64;epage=68;aulast=Kumari
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