Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

Correlation between auto/mitophagic processes and magnetic resonance imaging activity in multiple sclerosis patients

Abstract Background An alteration of autophagy and mitophagy, two highly conserved lysosome-dependent degradation pathways involved in the maintenance of cellular homeostasis, has been associated with multiple sclerosis (MS). Objective To search the level of autophagy-related 5 (ATG5) and Parkin pro...

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Bibliographic Details
Main Authors: Massimiliano Castellazzi, Simone Patergnani, Mariapina Donadio, Carlotta Giorgi, Massimo Bonora, Enrico Fainardi, Ilaria Casetta, Enrico Granieri, Maura Pugliatti, Paolo Pinton
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Autophagy
Mitophagy
Biomarkers
Magnetic resonance imaging
Online Access:http://link.springer.com/article/10.1186/s12974-019-1526-0

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