Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

ABSTRACT During tuberculosis, macrophages are critical for both pathogen survival and host immune activation. Since expression of particular cell surface markers reflects cell function, we used flow cytometry to measure the abundance of surface markers associated with polarity, lipid uptake, or patt...

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Bibliographic Details
Main Authors: Karim Lakehal, David Levine, Kathleen F. Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSphere
Subjects:
immunophenotyping
innate immunity
macrophage surface markers
pattern recognition receptors
tuberculosis biomarkers
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00475-17

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