Guidelines for in vitro simulated digestion and absorption of food

Abstract With the continuous improvement of people's living standards, food intake, bioactivity, and bioavailability have mainly concerned people. Therefore, the digestion and absorption of this kind of food have attracted people's attention. Some food has very high nutritional, medicinal,...

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Main Authors: Meili Xin, Min Zhao, Jinlong Tian, Bin Li
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Food Frontiers
Subjects:
Online Access:https://doi.org/10.1002/fft2.186
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author Meili Xin
Min Zhao
Jinlong Tian
Bin Li
author_facet Meili Xin
Min Zhao
Jinlong Tian
Bin Li
author_sort Meili Xin
collection DOAJ
description Abstract With the continuous improvement of people's living standards, food intake, bioactivity, and bioavailability have mainly concerned people. Therefore, the digestion and absorption of this kind of food have attracted people's attention. Some food has very high nutritional, medicinal, and medical value. However, because of its low conversion rate and utilization rate, the human body digests and absorbs less material, so the use of human value will be significantly reduced. Therefore, simulation and testing of digestion and absorption in vitro may be significant for dietary intake of bioactive substances. This paper reviews the organs and pathways of simulated food digestion and absorption in vitro and specific processing methods. In an in the vitro simulation system, the role of the human digestive system and absorption system in food digestion and absorption is described, and the performance of various simulation models, exceptionally dynamic in vitro models, is compared. Widespread use and refinement of these models will expand our understanding of the complex interplay of food substrates and digestive and absorptive systems. Therefore, it will be possible to design food with better bioavailability, more benefits to human health, and more targeted delivery, which is also in line with the development trend of food in the future.
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spelling doaj.art-54a3f55028d6443491fa94f2aa091e662023-03-27T16:55:06ZengWileyFood Frontiers2643-84292023-03-014152453210.1002/fft2.186Guidelines for in vitro simulated digestion and absorption of foodMeili Xin0Min Zhao1Jinlong Tian2Bin Li3College of Food Science Shenyang Agricultural University Shenyang Liaoning ChinaCollege of Food Science Shenyang Agricultural University Shenyang Liaoning ChinaCollege of Food Science Shenyang Agricultural University Shenyang Liaoning ChinaCollege of Food Science Shenyang Agricultural University Shenyang Liaoning ChinaAbstract With the continuous improvement of people's living standards, food intake, bioactivity, and bioavailability have mainly concerned people. Therefore, the digestion and absorption of this kind of food have attracted people's attention. Some food has very high nutritional, medicinal, and medical value. However, because of its low conversion rate and utilization rate, the human body digests and absorbs less material, so the use of human value will be significantly reduced. Therefore, simulation and testing of digestion and absorption in vitro may be significant for dietary intake of bioactive substances. This paper reviews the organs and pathways of simulated food digestion and absorption in vitro and specific processing methods. In an in the vitro simulation system, the role of the human digestive system and absorption system in food digestion and absorption is described, and the performance of various simulation models, exceptionally dynamic in vitro models, is compared. Widespread use and refinement of these models will expand our understanding of the complex interplay of food substrates and digestive and absorptive systems. Therefore, it will be possible to design food with better bioavailability, more benefits to human health, and more targeted delivery, which is also in line with the development trend of food in the future.https://doi.org/10.1002/fft2.186absorptiondigestionfoodin vitro
spellingShingle Meili Xin
Min Zhao
Jinlong Tian
Bin Li
Guidelines for in vitro simulated digestion and absorption of food
Food Frontiers
absorption
digestion
food
in vitro
title Guidelines for in vitro simulated digestion and absorption of food
title_full Guidelines for in vitro simulated digestion and absorption of food
title_fullStr Guidelines for in vitro simulated digestion and absorption of food
title_full_unstemmed Guidelines for in vitro simulated digestion and absorption of food
title_short Guidelines for in vitro simulated digestion and absorption of food
title_sort guidelines for in vitro simulated digestion and absorption of food
topic absorption
digestion
food
in vitro
url https://doi.org/10.1002/fft2.186
work_keys_str_mv AT meilixin guidelinesforinvitrosimulateddigestionandabsorptionoffood
AT minzhao guidelinesforinvitrosimulateddigestionandabsorptionoffood
AT jinlongtian guidelinesforinvitrosimulateddigestionandabsorptionoffood
AT binli guidelinesforinvitrosimulateddigestionandabsorptionoffood