Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy

ABSTRACT Mycobacterium tuberculosis (Mtb) continues to pose a significant threat to global health because it causes granulomas and systemic inflammatory responses during active tuberculosis (TB). Mtb can induce macrophage pyroptosis, which results in the release of IL-1β and causes tissue damage, th...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Bangzuo Ning, Jingjing Shen, Fanglin Liu, Hemin Zhang, Xin Jiang
التنسيق: مقال
اللغة:English
منشور في: American Society for Microbiology 2023-06-01
سلاسل:Microbiology Spectrum
الموضوعات:
الوصول للمادة أونلاين:https://journals.asm.org/doi/10.1128/spectrum.04711-22