Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
Paper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with...
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-07-01
|
Series: | Chemosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2227-9040/11/7/383 |
_version_ | 1797589821007331328 |
---|---|
author | Cong Chen Lulu Tian Wen Li Kun Wang Qijing Yang Jinying Lin Tianshou Zhang Biao Dong Lin Wang |
author_facet | Cong Chen Lulu Tian Wen Li Kun Wang Qijing Yang Jinying Lin Tianshou Zhang Biao Dong Lin Wang |
author_sort | Cong Chen |
collection | DOAJ |
description | Paper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with to use of paper-based sensors to manufacture a convenient and inexpensive disposable sensing device. This review focuses on the recent advances and progress in the design of paper-based salivary sensors and their applications. The first part mainly discusses various paper-based sensors and their advanced compositions, including dipstick assay, lateral flow assay, and microfluidic analytical device. Different detection methods in salivary biomarker detection are specially introduced in the secondary section, then their multiple potential applications and prospects are summarized. The sensor has excellent advantages for saliva detection, provides a reliable platform for point-of-care tests and telemedicine, and epically promotes the development of the medical Internet of Things. |
first_indexed | 2024-03-11T01:11:34Z |
format | Article |
id | doaj.art-54aba45ca8b64dd48c93cb2a5355fe08 |
institution | Directory Open Access Journal |
issn | 2227-9040 |
language | English |
last_indexed | 2024-03-11T01:11:34Z |
publishDate | 2023-07-01 |
publisher | MDPI AG |
record_format | Article |
series | Chemosensors |
spelling | doaj.art-54aba45ca8b64dd48c93cb2a5355fe082023-11-18T18:47:32ZengMDPI AGChemosensors2227-90402023-07-0111738310.3390/chemosensors11070383Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker DetectionCong Chen0Lulu Tian1Wen Li2Kun Wang3Qijing Yang4Jinying Lin5Tianshou Zhang6Biao Dong7Lin Wang8Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaPaper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with to use of paper-based sensors to manufacture a convenient and inexpensive disposable sensing device. This review focuses on the recent advances and progress in the design of paper-based salivary sensors and their applications. The first part mainly discusses various paper-based sensors and their advanced compositions, including dipstick assay, lateral flow assay, and microfluidic analytical device. Different detection methods in salivary biomarker detection are specially introduced in the secondary section, then their multiple potential applications and prospects are summarized. The sensor has excellent advantages for saliva detection, provides a reliable platform for point-of-care tests and telemedicine, and epically promotes the development of the medical Internet of Things.https://www.mdpi.com/2227-9040/11/7/383paper-based sensorsaliva biomarkerpoint of care |
spellingShingle | Cong Chen Lulu Tian Wen Li Kun Wang Qijing Yang Jinying Lin Tianshou Zhang Biao Dong Lin Wang Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection Chemosensors paper-based sensor saliva biomarker point of care |
title | Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection |
title_full | Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection |
title_fullStr | Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection |
title_full_unstemmed | Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection |
title_short | Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection |
title_sort | recent advances and perspectives regarding paper based sensors for salivary biomarker detection |
topic | paper-based sensor saliva biomarker point of care |
url | https://www.mdpi.com/2227-9040/11/7/383 |
work_keys_str_mv | AT congchen recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT lulutian recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT wenli recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT kunwang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT qijingyang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT jinyinglin recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT tianshouzhang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT biaodong recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection AT linwang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection |