Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection

Paper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with...

Full description

Bibliographic Details
Main Authors: Cong Chen, Lulu Tian, Wen Li, Kun Wang, Qijing Yang, Jinying Lin, Tianshou Zhang, Biao Dong, Lin Wang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/11/7/383
_version_ 1797589821007331328
author Cong Chen
Lulu Tian
Wen Li
Kun Wang
Qijing Yang
Jinying Lin
Tianshou Zhang
Biao Dong
Lin Wang
author_facet Cong Chen
Lulu Tian
Wen Li
Kun Wang
Qijing Yang
Jinying Lin
Tianshou Zhang
Biao Dong
Lin Wang
author_sort Cong Chen
collection DOAJ
description Paper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with to use of paper-based sensors to manufacture a convenient and inexpensive disposable sensing device. This review focuses on the recent advances and progress in the design of paper-based salivary sensors and their applications. The first part mainly discusses various paper-based sensors and their advanced compositions, including dipstick assay, lateral flow assay, and microfluidic analytical device. Different detection methods in salivary biomarker detection are specially introduced in the secondary section, then their multiple potential applications and prospects are summarized. The sensor has excellent advantages for saliva detection, provides a reliable platform for point-of-care tests and telemedicine, and epically promotes the development of the medical Internet of Things.
first_indexed 2024-03-11T01:11:34Z
format Article
id doaj.art-54aba45ca8b64dd48c93cb2a5355fe08
institution Directory Open Access Journal
issn 2227-9040
language English
last_indexed 2024-03-11T01:11:34Z
publishDate 2023-07-01
publisher MDPI AG
record_format Article
series Chemosensors
spelling doaj.art-54aba45ca8b64dd48c93cb2a5355fe082023-11-18T18:47:32ZengMDPI AGChemosensors2227-90402023-07-0111738310.3390/chemosensors11070383Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker DetectionCong Chen0Lulu Tian1Wen Li2Kun Wang3Qijing Yang4Jinying Lin5Tianshou Zhang6Biao Dong7Lin Wang8Department of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaState Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130021, ChinaDepartment of Oral Implantology, School and Hospital of Stomatology, Jilin University, Changchun 130021, ChinaPaper-based sensors overcome the drawbacks of conventional sensors in terms of their flexibility, portability, and stability compared to conventional sensors. Moreover, as a noninvasive bodily fluid, saliva contains various biomarkers related to physical status, which makes it perfectly matched with to use of paper-based sensors to manufacture a convenient and inexpensive disposable sensing device. This review focuses on the recent advances and progress in the design of paper-based salivary sensors and their applications. The first part mainly discusses various paper-based sensors and their advanced compositions, including dipstick assay, lateral flow assay, and microfluidic analytical device. Different detection methods in salivary biomarker detection are specially introduced in the secondary section, then their multiple potential applications and prospects are summarized. The sensor has excellent advantages for saliva detection, provides a reliable platform for point-of-care tests and telemedicine, and epically promotes the development of the medical Internet of Things.https://www.mdpi.com/2227-9040/11/7/383paper-based sensorsaliva biomarkerpoint of care
spellingShingle Cong Chen
Lulu Tian
Wen Li
Kun Wang
Qijing Yang
Jinying Lin
Tianshou Zhang
Biao Dong
Lin Wang
Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
Chemosensors
paper-based sensor
saliva biomarker
point of care
title Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
title_full Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
title_fullStr Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
title_full_unstemmed Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
title_short Recent Advances and Perspectives Regarding Paper-Based Sensors for Salivary Biomarker Detection
title_sort recent advances and perspectives regarding paper based sensors for salivary biomarker detection
topic paper-based sensor
saliva biomarker
point of care
url https://www.mdpi.com/2227-9040/11/7/383
work_keys_str_mv AT congchen recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT lulutian recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT wenli recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT kunwang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT qijingyang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT jinyinglin recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT tianshouzhang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT biaodong recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection
AT linwang recentadvancesandperspectivesregardingpaperbasedsensorsforsalivarybiomarkerdetection