HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform
The results of HPV detection in 550 cervical samples by cervical cytology were compared with the sequencing analysis and HPV genotyping 9G membrane test. The HPV genotyping 9G membrane test can efficiently identify and discriminate five HR-HPV genotypes. The 100% identical results of HPV genotypin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2014-10-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/14/10/19162 |
| _version_ | 1811184827577139200 |
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| author | Keumsoo Song Satish Balasaheb Nimse Heejung An Taisun Kim |
| author_facet | Keumsoo Song Satish Balasaheb Nimse Heejung An Taisun Kim |
| author_sort | Keumsoo Song |
| collection | DOAJ |
| description | The results of HPV detection in 550 cervical samples by cervical cytology were compared with the sequencing analysis and HPV genotyping 9G membrane test. The HPV genotyping 9G membrane test can efficiently identify and discriminate five HR-HPV genotypes. The 100% identical results of HPV genotyping 9G membrane tests with the sequencing results in 550 clinical samples ensure its wide clinical applicability. The simple handling steps and the portable scanning device make the HPV genotyping 9G membrane test applicable in point-of-care settings. Moreover, the HPV genotyping 9G membrane test allows one to obtain final results in 30 min at 25 °C by simply loading the hybridization and washing solution and scanning the membranes without any drying steps or special handling. The clinical sensitivity and specificity of the HPV genotyping 9G membrane test was found to be 100%, which is much higher than cervical cytology. |
| first_indexed | 2024-04-11T13:19:05Z |
| format | Article |
| id | doaj.art-54abb83e62ca4656a2e0f568cbd505c2 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T13:19:05Z |
| publishDate | 2014-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-54abb83e62ca4656a2e0f568cbd505c22022-12-22T04:22:16ZengMDPI AGSensors1424-82202014-10-011410191621917510.3390/s141019162s141019162HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic PlatformKeumsoo Song0Satish Balasaheb Nimse1Heejung An2Taisun Kim3Biometrix Technology, Inc. 202 BioVenture Plaza, Chuncheon 200-161, KoreaInstitute for Applied Chemistry and Department of Chemistry, Hallym University, Chuncheon 200-702, KoreaDepartment of Pathology, College of Medicine, CHA University, Seongnam 487-801, KoreaInstitute for Applied Chemistry and Department of Chemistry, Hallym University, Chuncheon 200-702, KoreaThe results of HPV detection in 550 cervical samples by cervical cytology were compared with the sequencing analysis and HPV genotyping 9G membrane test. The HPV genotyping 9G membrane test can efficiently identify and discriminate five HR-HPV genotypes. The 100% identical results of HPV genotyping 9G membrane tests with the sequencing results in 550 clinical samples ensure its wide clinical applicability. The simple handling steps and the portable scanning device make the HPV genotyping 9G membrane test applicable in point-of-care settings. Moreover, the HPV genotyping 9G membrane test allows one to obtain final results in 30 min at 25 °C by simply loading the hybridization and washing solution and scanning the membranes without any drying steps or special handling. The clinical sensitivity and specificity of the HPV genotyping 9G membrane test was found to be 100%, which is much higher than cervical cytology.http://www.mdpi.com/1424-8220/14/10/19162HPVhuman papillomavirusgenotypingcervical carcinomahybridization9G technologycervical cytology |
| spellingShingle | Keumsoo Song Satish Balasaheb Nimse Heejung An Taisun Kim HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform Sensors HPV human papillomavirus genotyping cervical carcinoma hybridization 9G technology cervical cytology |
| title | HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform |
| title_full | HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform |
| title_fullStr | HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform |
| title_full_unstemmed | HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform |
| title_short | HPV Genotyping 9G Membrane Test: A Point-of-Care Diagnostic Platform |
| title_sort | hpv genotyping 9g membrane test a point of care diagnostic platform |
| topic | HPV human papillomavirus genotyping cervical carcinoma hybridization 9G technology cervical cytology |
| url | http://www.mdpi.com/1424-8220/14/10/19162 |
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