Colony-stimulating factor-1 receptor inhibition combined with paclitaxel exerts effective antitumor effects in the treatment of ovarian cancer

Colony-stimulating factor-1 receptor inhibition combined with paclitaxel exerts effective antitumor effects in the treatment of ovarian cancer

Ovarian cancer is the tumor with the highest mortality among gynecological malignancies. Studies have confirmed that paclitaxel chemoresistance is associated with increased infiltration of tumor-associated macrophages (TAMs) in the microenvironment. Colony-stimulating factor 1 (CSF-1) receptor (CSF-...

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Bibliographic Details
Main Authors: Meijia Yu, Yiming Wu, Qingfang Li, Weiqi Hong, Yang Yang, Xiaoyi Hu, Yanfei Yang, Tianqi Lu, Xia Zhao, Xiawei Wei
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-05-01
Series:Genes and Diseases
Subjects:
CSF-1R
Ovarian cancer
Paclitaxel
PLX3397
Targeted therapy
Tumor-associated macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304223002349

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http://www.sciencedirect.com/science/article/pii/S2352304223002349

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