Poly (N-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles

Poly (N-vinylpyrrolidone) modification mitigates plasma protein corona formation on phosphomolybdate-based nanoparticles

Abstract Phosphomolybdate-based nanoparticles (PMo12-based NPs) have been commonly applied in nanomedicine. However, upon contact with biofluids, proteins are quickly adsorbed onto the NPs surface to form a protein corona, which induces the opsonization and facilitates the rapid clearance of the NPs...

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Bibliographic Details
Main Authors: Youyi Yu, Behafarid Ghalandari, Guangxia Shen, Liping Wang, Xiao Liu, Aiting Wang, Sijie Li, Haiyang Xie, Xianting Ding
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Journal of Nanobiotechnology
Subjects:
Phosphomolybdate
Zwitterionic polymer poly (N-vinylpyrrolidone)
Plasma protein corona
Mass spectrometry
Online Access:https://doi.org/10.1186/s12951-021-01140-8

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