Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses

Background: Pancreatic patient–derived organoids (PDOs) are a well-established model for studying pancreatic ductal adenocarcinoma (PDAC) carcinogenesis and are potential predictors of clinical responses to chemotherapy. Oncolytic virotherapy is envisioned as a novel treatment modality for pancreati...

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Bibliografiska uppgifter
Huvudupphovsmän:	Giulia Raimondi, Ana Mato-Berciano, Silvia Pascual-Sabater, Maria Rovira-Rigau, Miriam Cuatrecasas, Constantino Fondevila, Santiago Sánchez-Cabús, Harry Begthel, Sylvia F. Boj, Hans Clevers, Cristina Fillat
Materialtyp:	Artikel
Språk:	English
Publicerad:	Elsevier 2020-06-01
Serie:	EBioMedicine
Ämnen:	Pancreatic ductal adenocarcinoma (PDAC) Patient-derived organoids (PDO) Oncolytic adenovirus (OA) Orthotopic tumours
Länkar:	http://www.sciencedirect.com/science/article/pii/S2352396420301614

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