Wnt signaling in multiple myeloma: a central player in disease with therapeutic potential

Abstract Multiple myeloma is the second most frequent hematological malignancy in the western world and remains incurable, predominantly due to acquired drug resistance and disease relapse. The highly conserved Wnt signal transduction pathway, which plays a key role in regulating cellular processes...

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Détails bibliographiques
Auteurs principaux: Ingrid Spaan, Reinier A. Raymakers, Anja van de Stolpe, Victor Peperzak
Format: Article
Langue:English
Publié: BMC 2018-05-01
Collection:Journal of Hematology & Oncology
Sujets:
Accès en ligne:http://link.springer.com/article/10.1186/s13045-018-0615-3