Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism
We aimed to investigate correlation between perioperative biochemical values and adenoma volume, the effects of perioperative biochemical values and clinicopathological variables on postoperative hypocalcemia after parathyroidectomy. A retrospective study planned in tertiary university hospital on p...
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| Format: | Article |
| Language: | English |
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Society of Turaz Bilim
2023-03-01
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| Series: | Medicine Science |
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| Online Access: | https://www.medicinescience.org/?mno=129691 |
| _version_ | 1797316451524149248 |
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| author | Hakan Sivgin Mustafa Sami Bostan |
| author_facet | Hakan Sivgin Mustafa Sami Bostan |
| author_sort | Hakan Sivgin |
| collection | DOAJ |
| description | We aimed to investigate correlation between perioperative biochemical values and adenoma volume, the effects of perioperative biochemical values and clinicopathological variables on postoperative hypocalcemia after parathyroidectomy. A retrospective study planned in tertiary university hospital on patients undergone surgery for primer hyperparathyroidism. Preoperative calcium (first, close to surgery, maximum), PTH (first, close to surgery, maximum), alkaline phosphatase (ALP) and phosphorus (P) values, postoperative calcium (early, late), postoperative PTH (early, late), 24-hour urinary calcium calculation, time from the first diagnosis of elevated calcium until surgery, preoperative hypercalcemia treatments, excised parathyroid gland, histopathologic diagnosis, maximum diameter and volume of the excised parathyroid on histopathologic examination, postoperative intravenous calcium supplement were analyzed. 73 patients were included in the study. The median age of the patients was 54 years (range, 18-82), and 83.6% were female. In univariate analysis, patients who were administrated intravenous (IV) calcium supplement had higher preoperative PTH (p=0.024). adenoma volume correlated moderate with preoperative PTH first (r=0.396, p=0.001), preoperative maximum parathormone (r=0.380, p=0.001), preoperative PTH CS (r=0.432, p [Med-Science 2023; 12(1.000): 271-7] |
| first_indexed | 2024-03-08T03:19:32Z |
| format | Article |
| id | doaj.art-54b2f12bee20498b874ebd7bf4bc03d5 |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T03:19:32Z |
| publishDate | 2023-03-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-54b2f12bee20498b874ebd7bf4bc03d52024-02-12T10:34:08ZengSociety of Turaz BilimMedicine Science2147-06342023-03-01121271710.5455/medscience.2022.11.239129691Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidismHakan Sivgin0Mustafa Sami Bostan1Department of Internal Medicine, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey Department of General Surgery, Faculty of Medicine, Gaziosmanpasa University, Tokat, TurkeyWe aimed to investigate correlation between perioperative biochemical values and adenoma volume, the effects of perioperative biochemical values and clinicopathological variables on postoperative hypocalcemia after parathyroidectomy. A retrospective study planned in tertiary university hospital on patients undergone surgery for primer hyperparathyroidism. Preoperative calcium (first, close to surgery, maximum), PTH (first, close to surgery, maximum), alkaline phosphatase (ALP) and phosphorus (P) values, postoperative calcium (early, late), postoperative PTH (early, late), 24-hour urinary calcium calculation, time from the first diagnosis of elevated calcium until surgery, preoperative hypercalcemia treatments, excised parathyroid gland, histopathologic diagnosis, maximum diameter and volume of the excised parathyroid on histopathologic examination, postoperative intravenous calcium supplement were analyzed. 73 patients were included in the study. The median age of the patients was 54 years (range, 18-82), and 83.6% were female. In univariate analysis, patients who were administrated intravenous (IV) calcium supplement had higher preoperative PTH (p=0.024). adenoma volume correlated moderate with preoperative PTH first (r=0.396, p=0.001), preoperative maximum parathormone (r=0.380, p=0.001), preoperative PTH CS (r=0.432, p [Med-Science 2023; 12(1.000): 271-7]https://www.medicinescience.org/?mno=129691primer hyperparathyroidismcalcium supplementhypocalcemiaparathormoneadenoma volumehungry bone syndrome |
| spellingShingle | Hakan Sivgin Mustafa Sami Bostan Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism Medicine Science primer hyperparathyroidism calcium supplement hypocalcemia parathormone adenoma volume hungry bone syndrome |
| title | Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| title_full | Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| title_fullStr | Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| title_full_unstemmed | Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| title_short | Preoperative biochemical values are correlated with adenoma volume, but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| title_sort | preoperative biochemical values are correlated with adenoma volume but not predictive factors for hungry bone syndrome in patients with primary hyperparathyroidism |
| topic | primer hyperparathyroidism calcium supplement hypocalcemia parathormone adenoma volume hungry bone syndrome |
| url | https://www.medicinescience.org/?mno=129691 |
| work_keys_str_mv | AT hakansivgin preoperativebiochemicalvaluesarecorrelatedwithadenomavolumebutnotpredictivefactorsforhungrybonesyndromeinpatientswithprimaryhyperparathyroidism AT mustafasamibostan preoperativebiochemicalvaluesarecorrelatedwithadenomavolumebutnotpredictivefactorsforhungrybonesyndromeinpatientswithprimaryhyperparathyroidism |