Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S
This study shows the possibility of determining the (NAP) in its pure state and in Pharmaceuticals using Chrome Azrol S Reagent . This spectral method was based on the formation of a colored violet complex at pH=3.5 , The complex has a maximum absorbance value at a wavelength of 545nm. The relations...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Arabic |
| Published: |
Tishreen University
2019-09-01
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| Series: | مجلة جامعة تشرين للبحوث والدراسات العلمية، سلسلة العلوم الأساسية |
| Online Access: | http://www.journal.tishreen.edu.sy/index.php/bassnc/article/view/9002 |
| _version_ | 1797419499636391936 |
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| author | Malek Okdeh Juhaina Dib Mohammad Obeid |
| author_facet | Malek Okdeh Juhaina Dib Mohammad Obeid |
| author_sort | Malek Okdeh |
| collection | DOAJ |
| description | This study shows the possibility of determining the (NAP) in its pure state and in Pharmaceuticals using Chrome Azrol S Reagent . This spectral method was based on the formation of a colored violet complex at pH=3.5 , The complex has a maximum absorbance value at a wavelength of 545nm. The relationship between absorbance and naproxine concentrations was linear. The Beer-Lambert’s law is within the range of concentrations between (2.306-46.047) µg/ml and with a Relative percentage standard deviation of 1.288 and with a correlation coefficient of R2=0.9987 and a molar absorption coefficient of (1.15×104( L.mol-1.cm-1.The detection limit of naproxen was 0.5873, and the results indicated that the presence of adjuvants does not affect the determination process of naproxen.
The analytical results were characterized by a good selectivity, accuracy and sensitivity to the identification of some active substances in its pure state and pharmaceuticals, at a lower cost than the approved constitutional methods
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| first_indexed | 2024-03-09T06:48:11Z |
| format | Article |
| id | doaj.art-54b383b0752e4f3cb1764024abf95423 |
| institution | Directory Open Access Journal |
| issn | 2079-3057 2663-4252 |
| language | Arabic |
| last_indexed | 2024-03-09T06:48:11Z |
| publishDate | 2019-09-01 |
| publisher | Tishreen University |
| record_format | Article |
| series | مجلة جامعة تشرين للبحوث والدراسات العلمية، سلسلة العلوم الأساسية |
| spelling | doaj.art-54b383b0752e4f3cb1764024abf954232023-12-03T10:31:50ZaraTishreen Universityمجلة جامعة تشرين للبحوث والدراسات العلمية، سلسلة العلوم الأساسية2079-30572663-42522019-09-01414Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol SMalek Okdeh Juhaina Dib Mohammad Obeid This study shows the possibility of determining the (NAP) in its pure state and in Pharmaceuticals using Chrome Azrol S Reagent . This spectral method was based on the formation of a colored violet complex at pH=3.5 , The complex has a maximum absorbance value at a wavelength of 545nm. The relationship between absorbance and naproxine concentrations was linear. The Beer-Lambert’s law is within the range of concentrations between (2.306-46.047) µg/ml and with a Relative percentage standard deviation of 1.288 and with a correlation coefficient of R2=0.9987 and a molar absorption coefficient of (1.15×104( L.mol-1.cm-1.The detection limit of naproxen was 0.5873, and the results indicated that the presence of adjuvants does not affect the determination process of naproxen. The analytical results were characterized by a good selectivity, accuracy and sensitivity to the identification of some active substances in its pure state and pharmaceuticals, at a lower cost than the approved constitutional methods http://www.journal.tishreen.edu.sy/index.php/bassnc/article/view/9002 |
| spellingShingle | Malek Okdeh Juhaina Dib Mohammad Obeid Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S مجلة جامعة تشرين للبحوث والدراسات العلمية، سلسلة العلوم الأساسية |
| title | Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S |
| title_full | Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S |
| title_fullStr | Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S |
| title_full_unstemmed | Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S |
| title_short | Determination of Naproxine in its pure form and in some Pharmaceuticals by vis-Spectrophotometry using the Chrome Azrol S |
| title_sort | determination of naproxine in its pure form and in some pharmaceuticals by vis spectrophotometry using the chrome azrol s |
| url | http://www.journal.tishreen.edu.sy/index.php/bassnc/article/view/9002 |
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