Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model

Freeze-thaw decellularization of the trabecular meshwork in an ex vivo eye perfusion model

Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced by ablating cells with suicide gene t...

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Bibliographic Details
Main Authors: Yalong Dang, Susannah Waxman, Chao Wang, Adrianna Jensen, Ralitsa T. Loewen, Richard A. Bilonick, Nils A. Loewen
Format: Article
Language:English
Published: PeerJ Inc. 2017-08-01
Series:PeerJ
Subjects:
Trabecular meshwork
Decellularization
Glaucoma
Pig eyes
Ablation
Intraocular pressure
Online Access:https://peerj.com/articles/3629.pdf

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