Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil
A transversal study was conducted among 472 vulnerable individuals (recyclable waste pickers, immigrants and refugees, homeless individuals, as well as lesbian, gay, bisexual, and transexual individuals) in Goiânia City, the capital of the State of Goiás, Brazil, to investigate the prevalence of hep...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/15/10/2070 |
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| author | Sheila Araújo Teles Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Livia Melo Villar Jeanne-Marie Stacciarini Regina Maria Bringel Martins |
| author_facet | Sheila Araújo Teles Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Livia Melo Villar Jeanne-Marie Stacciarini Regina Maria Bringel Martins |
| author_sort | Sheila Araújo Teles |
| collection | DOAJ |
| description | A transversal study was conducted among 472 vulnerable individuals (recyclable waste pickers, immigrants and refugees, homeless individuals, as well as lesbian, gay, bisexual, and transexual individuals) in Goiânia City, the capital of the State of Goiás, Brazil, to investigate the prevalence of hepatitis E virus (HEV) infection. A total of 459 (97.2%) serum samples were tested for anti-HEV IgG and IgM antibodies using fully automated chemiluminescence immunoassays (Liaison<sup>®</sup> Murex Anti-HEV IgG and IgM assays, DiaSorin, Saluggia, Italy). Positive samples were tested for the presence of HEV RNA by a real-time polymerase chain reaction. A seroprevalence of 0.87% (95% confidence interval [CI]: 0.34–2.22) was found for anti-HEV IgG. Furthermore, anti-HEV IgM was detected in only one individual (0.22%; 95% CI: 0.04–1.22), who was also negative for HEV RNA. These findings revealed that HEV infection is infrequent in vulnerable individuals in Central Brazil, with low seroprevalence of past and recent HEV infections. |
| first_indexed | 2024-03-10T20:49:49Z |
| format | Article |
| id | doaj.art-54b69563061d4352baf6b03324769e9b |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T20:49:49Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-54b69563061d4352baf6b03324769e9b2023-11-19T18:27:49ZengMDPI AGViruses1999-49152023-10-011510207010.3390/v15102070Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central BrazilSheila Araújo Teles0Karlla Antonieta Amorim Caetano1Megmar Aparecida dos Santos Carneiro2Livia Melo Villar3Jeanne-Marie Stacciarini4Regina Maria Bringel Martins5Faculty of Nursing, Federal University of Goias, Goiania 74605-080, BrazilFaculty of Nursing, Federal University of Goias, Goiania 74605-080, BrazilInstitute of Tropical Medicine and Public Health, Federal University of Goias, Goiania 74605-050, BrazilViral Hepatitis Laboratory, Oswaldo Cruz Institute, Rio de Janeiro 21045-900, BrazilCollege of Nursing, University of Florida, Gainesville, FL 32610-0197, USAInstitute of Tropical Medicine and Public Health, Federal University of Goias, Goiania 74605-050, BrazilA transversal study was conducted among 472 vulnerable individuals (recyclable waste pickers, immigrants and refugees, homeless individuals, as well as lesbian, gay, bisexual, and transexual individuals) in Goiânia City, the capital of the State of Goiás, Brazil, to investigate the prevalence of hepatitis E virus (HEV) infection. A total of 459 (97.2%) serum samples were tested for anti-HEV IgG and IgM antibodies using fully automated chemiluminescence immunoassays (Liaison<sup>®</sup> Murex Anti-HEV IgG and IgM assays, DiaSorin, Saluggia, Italy). Positive samples were tested for the presence of HEV RNA by a real-time polymerase chain reaction. A seroprevalence of 0.87% (95% confidence interval [CI]: 0.34–2.22) was found for anti-HEV IgG. Furthermore, anti-HEV IgM was detected in only one individual (0.22%; 95% CI: 0.04–1.22), who was also negative for HEV RNA. These findings revealed that HEV infection is infrequent in vulnerable individuals in Central Brazil, with low seroprevalence of past and recent HEV infections.https://www.mdpi.com/1999-4915/15/10/2070hepatitis E virusvulnerable populationsprevalenceBrazil |
| spellingShingle | Sheila Araújo Teles Karlla Antonieta Amorim Caetano Megmar Aparecida dos Santos Carneiro Livia Melo Villar Jeanne-Marie Stacciarini Regina Maria Bringel Martins Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil Viruses hepatitis E virus vulnerable populations prevalence Brazil |
| title | Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil |
| title_full | Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil |
| title_fullStr | Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil |
| title_full_unstemmed | Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil |
| title_short | Hepatitis E Prevalence in Vulnerable Populations in Goiânia, Central Brazil |
| title_sort | hepatitis e prevalence in vulnerable populations in goiania central brazil |
| topic | hepatitis E virus vulnerable populations prevalence Brazil |
| url | https://www.mdpi.com/1999-4915/15/10/2070 |
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