Altered metabolism and persistent starvation behaviors caused by reduced AMPK function in Drosophila.

Altered metabolism and persistent starvation behaviors caused by reduced AMPK function in Drosophila.

Organisms must utilize multiple mechanisms to maintain energetic homeostasis in the face of limited nutrient availability. One mechanism involves activation of the heterotrimeric AMP-activated protein kinase (AMPK), a cell-autonomous sensor to energetic changes regulated by ATP to AMP ratios. We exa...

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Bibliographic Details
Main Authors: Erik C Johnson, Nevzat Kazgan, Colin A Bretz, Lawrence J Forsberg, Clare E Hector, Ryan J Worthen, Rob Onyenwoke, Jay E Brenman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2942814?pdf=render

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