Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China
Abstract Background The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) epidemics. However, the effectiveness of GACP in HIV prevention...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Public Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12889-024-18345-9 |
| _version_ | 1827315671738875904 |
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| author | Ping Cen Guo Xu Jianxun Wu Jiao Qin Jinfeng He Xiaofang Deng Xi Yang Peng Lu Mengni Nong Junjun Jiang Li Ye Hongyang Tang Bingyu Liang Hao Liang |
| author_facet | Ping Cen Guo Xu Jianxun Wu Jiao Qin Jinfeng He Xiaofang Deng Xi Yang Peng Lu Mengni Nong Junjun Jiang Li Ye Hongyang Tang Bingyu Liang Hao Liang |
| author_sort | Ping Cen |
| collection | DOAJ |
| description | Abstract Background The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) epidemics. However, the effectiveness of GACP in HIV prevention and treatment has rarely been reported. This study aimed to assess the effectiveness of the GACP implemented in Guangxi, China and provide data for strategy and praxis improvements to achieve Joint United Nations Programme on HIV/AIDS (UNAIDS) 95-95 targets. Methods We used spatial approaches to trace the spatiotemporal distribution properties, epidemic trends, and correlation between macroscopic factors and HIV incidence using data from the Chinese HIV/AIDS case reporting system to explore the effects of the GACP. Results During the GACP era, the HIV epidemic stabilized in urban centers, showing a downward trend in the Hengzhou and Binyang Counties in the eastern region, whereas it continued to increase in rural areas of the northwest region, such as the Long’an, Mashan, Shanglin, and Wuming Districts. The linear directional mean (LDM) of HIV infection reported cases displayed a southeast–northwest direction, with an LDM value of 12.52°. Compared with that in Phase I, Hengzhou withdrew from the high-high clustering area, and the west–north suburban counties pulled out the low-low clustering area during Phase II. Significant HIV clusters were identified in the eastern region during Phase I, whereas these clusters emerged in the northwestern areas during Phase II. Regarding HIV, socioeconomic status, population mobility, and medical care levels were the key social drivers of heterogeneous spatial distribution. Conclusions The GACP assisted in effectively managing the HIV epidemic in urban and eastern areas of Nanning City. However, prevention and control efforts in rural regions, particularly those located in the northwest, may not have yielded comparable outcomes. To address this disparity, allocating additional resources and implementing tailored intervention measures for these rural areas are imperative. |
| first_indexed | 2024-04-24T23:01:27Z |
| format | Article |
| id | doaj.art-54bc92e283d94debaf8a98105548a686 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-24T23:01:27Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-54bc92e283d94debaf8a98105548a6862024-03-17T12:41:04ZengBMCBMC Public Health1471-24582024-03-0124111110.1186/s12889-024-18345-9Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, ChinaPing Cen0Guo Xu1Jianxun Wu2Jiao Qin3Jinfeng He4Xiaofang Deng5Xi Yang6Peng Lu7Mengni Nong8Junjun Jiang9Li Ye10Hongyang Tang11Bingyu Liang12Hao Liang13Nanning Center for Disease Control and PreventionNanning Survey and Design Institute Group Co., Ltd.Nanning Survey and Design Institute Group Co., Ltd.Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityNanning Center for Disease Control and PreventionNanning Center for Disease Control and PreventionNanning Survey and Design Institute Group Co., Ltd.Nanning Center for Disease Control and PreventionGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityNanning Center for Disease Control and PreventionGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityGuangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical UniversityAbstract Background The Guangxi government initiated two rounds of the Guangxi AIDS Conquering Project (GACP) in 2010 (Phase I) and 2015 (Phase II) to control human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) epidemics. However, the effectiveness of GACP in HIV prevention and treatment has rarely been reported. This study aimed to assess the effectiveness of the GACP implemented in Guangxi, China and provide data for strategy and praxis improvements to achieve Joint United Nations Programme on HIV/AIDS (UNAIDS) 95-95 targets. Methods We used spatial approaches to trace the spatiotemporal distribution properties, epidemic trends, and correlation between macroscopic factors and HIV incidence using data from the Chinese HIV/AIDS case reporting system to explore the effects of the GACP. Results During the GACP era, the HIV epidemic stabilized in urban centers, showing a downward trend in the Hengzhou and Binyang Counties in the eastern region, whereas it continued to increase in rural areas of the northwest region, such as the Long’an, Mashan, Shanglin, and Wuming Districts. The linear directional mean (LDM) of HIV infection reported cases displayed a southeast–northwest direction, with an LDM value of 12.52°. Compared with that in Phase I, Hengzhou withdrew from the high-high clustering area, and the west–north suburban counties pulled out the low-low clustering area during Phase II. Significant HIV clusters were identified in the eastern region during Phase I, whereas these clusters emerged in the northwestern areas during Phase II. Regarding HIV, socioeconomic status, population mobility, and medical care levels were the key social drivers of heterogeneous spatial distribution. Conclusions The GACP assisted in effectively managing the HIV epidemic in urban and eastern areas of Nanning City. However, prevention and control efforts in rural regions, particularly those located in the northwest, may not have yielded comparable outcomes. To address this disparity, allocating additional resources and implementing tailored intervention measures for these rural areas are imperative.https://doi.org/10.1186/s12889-024-18345-9The Guangxi AIDS conquering projectGeospatial approachHeterogeneous spatial distributionHuman immunodeficiency virusAcquired immunodeficiency syndrome |
| spellingShingle | Ping Cen Guo Xu Jianxun Wu Jiao Qin Jinfeng He Xiaofang Deng Xi Yang Peng Lu Mengni Nong Junjun Jiang Li Ye Hongyang Tang Bingyu Liang Hao Liang Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China BMC Public Health The Guangxi AIDS conquering project Geospatial approach Heterogeneous spatial distribution Human immunodeficiency virus Acquired immunodeficiency syndrome |
| title | Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China |
| title_full | Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China |
| title_fullStr | Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China |
| title_full_unstemmed | Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China |
| title_short | Effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in Nanning, China |
| title_sort | effectiveness of human immunodeficiency virus prevention strategies by mapping the geographic dispersion pattern of human immunodeficiency virus prevalence in nanning china |
| topic | The Guangxi AIDS conquering project Geospatial approach Heterogeneous spatial distribution Human immunodeficiency virus Acquired immunodeficiency syndrome |
| url | https://doi.org/10.1186/s12889-024-18345-9 |
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