The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importance of this oncogenic protein in disease pathogenesis....

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Alexandra M Davis, Abigail Rapley, Christopher W Dawson, Lawrence S Young, Mhairi A Morris
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2021-08-01
Schriftenreihe:Pathogens
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Online Zugang:https://www.mdpi.com/2076-0817/10/8/982