The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

The EBV-Encoded Oncoprotein, LMP1, Recruits and Transforms Fibroblasts via an ERK-MAPK-Dependent Mechanism

Latent membrane protein 1 (LMP1), the major oncoprotein encoded by Epstein–Barr virus (EBV), is expressed at widely variable levels in undifferentiated nasopharyngeal carcinoma (NPC) biopsies, fueling intense debate in the field as to the importance of this oncogenic protein in disease pathogenesis....

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Alexandra M Davis, Abigail Rapley, Christopher W Dawson, Lawrence S Young, Mhairi A Morris
Format: Artykuł
Język:English
Wydane: MDPI AG 2021-08-01
Seria:Pathogens
Hasła przedmiotowe:
LMP1
EBV
NPC
fibroblast
myofibroblast
cancer-associated fibroblasts
Dostęp online:https://www.mdpi.com/2076-0817/10/8/982

Internet

https://www.mdpi.com/2076-0817/10/8/982

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