The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response

The Intra- and Extra-Telomeric Role of TRF2 in the DNA Damage Response

Telomere repeat binding factor 2 (TRF2) has a well-known function at the telomeres, which acts to protect the telomere end from being recognized as a DNA break or from unwanted recombination. This protection mechanism prevents DNA instability from mutation and subsequent severe diseases caused by th...

Full description

Bibliographic Details
Main Authors: Siti A. M. Imran, Muhammad Dain Yazid, Wei Cui, Yogeswaran Lokanathan
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
TRF2
DNA damage response
telomeres protection
extra-telomeric
Online Access:https://www.mdpi.com/1422-0067/22/18/9900

Similar Items

Similar Items