Evaluation of Tear Function Tests and Lower Tear Meniscus Height in Keratoconus Patients
Pur po se: To assess the tear function tests and the lower tear meniscus height (LTMH) in keratoconus patients and to evaluate the relationship of these parameters with the progression of keratoconus. Ma te ri al and Met hod: Thirty-eight eyes (group 1) of 21 keratoconus patients and 36 eyes (grou...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2012-07-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.oftalmoloji.org/article_2168/Evaluation-Of-Tear-Function-Tests-And-Lower-Tear-Meniscus-Height-In-Keratoconus-Patients |
| Summary: | Pur po se: To assess the tear function tests and the lower tear meniscus height (LTMH) in keratoconus patients and to evaluate the
relationship of these parameters with the progression of keratoconus.
Ma te ri al and Met hod: Thirty-eight eyes (group 1) of 21 keratoconus patients and 36 eyes (group 2) of 18 healthy subjects were
included in this prospective study. Both groups underwent corneal topographic and keratometric measurements, tear break-up time
(T-BUT) and Schirmer tests as well as measurement of the LTMH with anterior segment optic coherence tomography (OCT) after the
ophthalmologic examination. The values obtained from both groups were compared and evaluated for statistical significance and
reliability.
Re sults: There was no statistically significant difference between the two groups in terms of age and gender (p>0.05). The mean Schirmer test
values were 14.87±8.9 mm and 16.77±8.1 mm in group 1 and group 2, respectively (p=0.367). There was not any correlation between the
keratometric power and the Schirmer test in group 1 and group 2 (group 1: r=0.114, p=0.548, group 2: r=0.151, p=0.972). The mean TBUT
value was 12.83±7.3 sec in group 1, and 18.25±8.5 sec in group 2 (p=0.018). There was a negative correlation between keratometric power
and TBUT in group 1, while there was no correlation in group 2 (group 1: r=0.717, p=0.001, group 2: r=0.235, p=0.212). The mean LTMH
was 265.30±112 µm in group 1 and 313.29±167 µm in group 2 (p=0.151). There was no correlation between keratometric power and LTMH
in both groups (group 1: r=0.001, p=0.997, group 2: r=0.318, p=0.130).
Dis cus si on: In this study, it was shown that keratoconus patients have normal tear volume but reduced tear film stability compared
to healthy individuals and this reduction is relate to the progression of keratoconus. (Turk J Ophthalmol 2012; 42: 249-52) |
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| ISSN: | 1300-0659 2147-2661 |