Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore

Single-molecule fingerprinting of protein-drug interaction using a funneled biological nanopore

Efficient screening of protein-drug interactions (PDIs) has been impeded by the limitations of current biophysical approaches. Here, the authors present a funneled YaxAB nanopore sensor which allows label-free, single-molecule detection of proteins and PDIs.

Bibliographic Details
Main Authors: Ki-Baek Jeong, Minju Ryu, Jin-Sik Kim, Minsoo Kim, Jejoong Yoo, Minji Chung, Sohee Oh, Gyunghee Jo, Seong-Gyu Lee, Ho Min Kim, Mi-Kyung Lee, Seung-Wook Chi
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37098-4

Internet

https://doi.org/10.1038/s41467-023-37098-4

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