Lithium Attenuates Cannabinoid-Induced Dependence in the Animal Model: Involvement of Phosphorylated ERK1/2 and GSK-3β Signaling Pathways

Lithium Attenuates Cannabinoid-Induced Dependence in the Animal Model: Involvement of Phosphorylated ERK1/2 and GSK-3β Signaling Pathways

Cannabis is one of the most banned drugs in the world. Cannabinoid-induced dependence or withdrawal signs are indicated by the result of complex molecular mechanisms including upstream protein kinases (PKs), such as an extracellular signal regulated kinase1/2 (ERK1/2) and downstream glycogen synthas...

Full description

Bibliographic Details
Main Authors: Hamid Reza Rahimi, Ahmad Reza Dehpour, Shahram Ejtemaei Mehr, Mohammad Sharifzadeh, Mohammad Hossein Ghahremani, Ali Razmi, Seyed Nasser Ostad
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2014-09-01
Series:Acta Medica Iranica
Subjects:
Protein kinase
Cannabinoid receptor
WIN 55
212- 2
Neuroprotection
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4668

Similar Items

Similar Items