Medical, pharmaceutical, and biomedical applications of chitosan: A review

Chitosan is a biopolymer chitin derivative discovered in 1811 by Henri Braconnot, and it was first used in 1985 by Charles Rouget. It is produced via the deacetylation of chitin (the natural component of the arthropods exoskeletons and the fungal cell wall). The unique solubility and the chemical an...

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Main Author: Rasha A F Jasim
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Medical Journal of Babylon
Subjects:
Online Access:http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=291;epage=294;aulast=Jasim
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author Rasha A F Jasim
author_facet Rasha A F Jasim
author_sort Rasha A F Jasim
collection DOAJ
description Chitosan is a biopolymer chitin derivative discovered in 1811 by Henri Braconnot, and it was first used in 1985 by Charles Rouget. It is produced via the deacetylation of chitin (the natural component of the arthropods exoskeletons and the fungal cell wall). The unique solubility and the chemical and biological characterization of chitosan attracted more scientific and industrial attention, specifically in the past 20 years. Its properties depend on the degree of deacetylation and its molecular weight. Therefore, recently, different forms of chitosan (solutions, suspension, gels/hydrogels, sponges, microparticles/nanoparticles, membranes and films, fibers/nanofibers) and its derivatives have been used in many fields. It has a wide range of applications in various fields, such as medicine, industry, agriculture, and commercial research. Medicinally, because of its biocompatibility, biodegradability, nontoxicity, natural origin, and similarity with human macromolecules, chitosan is widely used in pharmaceutical applications, antimicrobial applications, gene delivery, gene therapy, wound healing and burns, regenerative medicine, tissue engineering, cancer applications, dermatology, ophthalmology, dentistry, biosensors, as well as bioimaging, support for immobilized enzymes, and veterinary medicine. In this review, some medicinal applications of chitosan will be highlighted.
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spelling doaj.art-54ca2a384a3b43b693f01ec33c6c43b32022-12-21T19:38:30ZengWolters Kluwer Medknow PublicationsMedical Journal of Babylon1812-156X2312-67602021-01-0118429129410.4103/MJBL.MJBL_45_21Medical, pharmaceutical, and biomedical applications of chitosan: A reviewRasha A F JasimChitosan is a biopolymer chitin derivative discovered in 1811 by Henri Braconnot, and it was first used in 1985 by Charles Rouget. It is produced via the deacetylation of chitin (the natural component of the arthropods exoskeletons and the fungal cell wall). The unique solubility and the chemical and biological characterization of chitosan attracted more scientific and industrial attention, specifically in the past 20 years. Its properties depend on the degree of deacetylation and its molecular weight. Therefore, recently, different forms of chitosan (solutions, suspension, gels/hydrogels, sponges, microparticles/nanoparticles, membranes and films, fibers/nanofibers) and its derivatives have been used in many fields. It has a wide range of applications in various fields, such as medicine, industry, agriculture, and commercial research. Medicinally, because of its biocompatibility, biodegradability, nontoxicity, natural origin, and similarity with human macromolecules, chitosan is widely used in pharmaceutical applications, antimicrobial applications, gene delivery, gene therapy, wound healing and burns, regenerative medicine, tissue engineering, cancer applications, dermatology, ophthalmology, dentistry, biosensors, as well as bioimaging, support for immobilized enzymes, and veterinary medicine. In this review, some medicinal applications of chitosan will be highlighted.http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=291;epage=294;aulast=Jasimapplication of chitosanbenefit of chitosanbiomedicalchitosanpharmaceutical
spellingShingle Rasha A F Jasim
Medical, pharmaceutical, and biomedical applications of chitosan: A review
Medical Journal of Babylon
application of chitosan
benefit of chitosan
biomedical
chitosan
pharmaceutical
title Medical, pharmaceutical, and biomedical applications of chitosan: A review
title_full Medical, pharmaceutical, and biomedical applications of chitosan: A review
title_fullStr Medical, pharmaceutical, and biomedical applications of chitosan: A review
title_full_unstemmed Medical, pharmaceutical, and biomedical applications of chitosan: A review
title_short Medical, pharmaceutical, and biomedical applications of chitosan: A review
title_sort medical pharmaceutical and biomedical applications of chitosan a review
topic application of chitosan
benefit of chitosan
biomedical
chitosan
pharmaceutical
url http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2021;volume=18;issue=4;spage=291;epage=294;aulast=Jasim
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