An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example

An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example

Abstract Background Target identification is necessary for the comprehensive inference of the mechanism of action of a compound. The application of computational methods to predict the targets of bioactive compounds saves cost and time in drug research and development. Therefore, we designed an inte...

Full description

Bibliographic Details
Main Authors: Hao Sun, Yiting Shen, Guangwen Luo, Yuepiao Cai, Zheng Xiang
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Bioinformatics
Subjects:
Target identification
Rhein
Ligand-protein docking
Network analysis
Enrichment analysis
SPR
Online Access:http://link.springer.com/article/10.1186/s12859-018-2346-4

Similar Items

Similar Items