A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus

A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus

Vaccination remains the most effective approach for preventing and controlling equine influenza virus (EIV) in horses. However, the ongoing evolution of EIV has increased the genetic and antigenic differences between currently available vaccines and circulating strains, resulting in suboptimal vacci...

Full description

Bibliographic Details
Main Authors:	Pilar Blanco-Lobo, Laura Rodriguez, Stephanie Reedy, Fatai S. Oladunni, Aitor Nogales, Pablo R. Murcia, Thomas M. Chambers, Luis Martinez-Sobrido
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Viruses
Subjects:	equine influenza virus live-attenuated influenza vaccine master donor virus reverse genetics techniques recombinant virus
Online Access:	https://www.mdpi.com/1999-4915/11/10/933

Similar Items

Novel Approaches for The Development of Live Attenuated Influenza Vaccines
by: Pilar Blanco-Lobo, et al.
Published: (2019-02-01)

Temperature Sensitive Mutations in Influenza A Viral Ribonucleoprotein Complex Responsible for the Attenuation of the Live Attenuated Influenza Vaccine
by: Luis Martínez-Sobrido, et al.
Published: (2018-10-01)

Mutation L319Q in the PB1 Polymerase Subunit Improves Attenuation of a Candidate Live-Attenuated Influenza A Virus Vaccine
by: Aitor Nogales, et al.
Published: (2022-06-01)

Equine Influenza Virus and Vaccines
by: Fatai S. Oladunni, et al.
Published: (2021-08-01)

Increasing the Safety Profile of the Master Donor Live Attenuated Influenza Vaccine
by: Thomas A. Hilimire, et al.
Published: (2020-01-01)

Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile
by: Nicolas Bravo-Vasquez, et al.
Published: (2020-12-01)

Equine influenza in Brazil
by: Patricia Filippsen Favaro, et al.
Published: (2016-06-01)

Development of Cross-Reactive Live Attenuated Influenza Vaccine Candidates against Both Lineages of Influenza B Virus
by: Pei-Fong Wong, et al.
Published: (2024-01-01)

A New Master Donor Virus for the Development of Live-Attenuated Influenza B Virus Vaccines
by: Chantelle L. White, et al.
Published: (2021-06-01)

Evaluation of concurrent vaccinations with recombinant canarypox equine influenza virus and inactivated equine herpesvirus vaccines
by: Dong-Ha Lee, et al.
Published: (2022-05-01)

Replication-Competent Influenza A Viruses Expressing Reporter Genes
by: Michael Breen, et al.
Published: (2016-06-01)

Serological, molecular characterization and epidemiological situation of equine influenza in the Arabic Maghreb countries between 1972 to 2010
by: Mohamed Boukharta, et al.
Published: (2014-08-01)

Equine Influenza Virus—A Neglected, Reemergent Disease Threat
by: Alexandra Sack, et al.
Published: (2019-06-01)

The Optimisation of Pseudotyped Viruses for the Characterisation of Immune Responses to Equine Influenza Virus
by: Simon D. Scott, et al.
Published: (2016-12-01)

Genetic analysis of the M gene of equine influenza virus strains isolated in Poland, in the context of the Asian-like group formation
by: Kwaśnik Małgorzata, et al.
Published: (2018-12-01)

Global epidemiology of Equine Influenza viruses; “A possible emerging zoonotic threat in future” an extensive systematic review with evidence
by: A. Khan, et al.
Published: (2021-08-01)

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection
by: Rebecca Kinsley, et al.
Published: (2020-08-01)

Developments in Avian Influenza Virus Vaccines
by: Ellen W. Collisson, et al.
Published: (2007-07-01)

Genetic and serologic surveillance of canine (CIV) and equine (EIV) influenza virus in Nuevo León State, México
by: Claudia B. Plata-Hipólito, et al.
Published: (2019-12-01)

Safety, Immunogenicity, and Protective Efficacy of a Chimeric A/B Live Attenuated Influenza Vaccine in a Mouse Model
by: Ekaterina Stepanova, et al.
Published: (2021-01-01)

Highly reproductive attenuated H2N2 and H7N9 reassortants on the basis of A/Hong Kong/1/68/162/35 donor virus
by: I. G. Vidyaeva, et al.
Published: (2016-12-01)

A Comprehensive Review on Equine Influenza Virus: Etiology, Epidemiology, Pathobiology, Advances in Developing Diagnostics, Vaccines, and Control Strategies
by: Raj K. Singh, et al.
Published: (2018-09-01)

Expression of the SARS-CoV-2 receptor-binding domain by live attenuated influenza vaccine virus as a strategy for designing a bivalent vaccine against COVID-19 and influenza
by: Ekaterina Stepanova, et al.
Published: (2024-04-01)

Generation and Characterization of Universal Live-Attenuated Influenza Vaccine Candidates Containing Multiple M2e Epitopes
by: Tatiana Kotomina, et al.
Published: (2020-11-01)

Equine Influenza A(H3N8) Virus Infection in Cats
by: Shuo Su, et al.
Published: (2014-12-01)

A Strategy to Elicit M2e-Specific Antibodies Using a Recombinant H7N9 Live Attenuated Influenza Vaccine Expressing Multiple M2e Tandem Repeats
by: Daria Mezhenskaya, et al.
Published: (2021-02-01)

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines
by: Laura Rodriguez, et al.
Published: (2019-10-01)

Live attenuated influenza A virus vaccines with modified NS1 proteins for veterinary use
by: Aitor Nogales, et al.
Published: (2022-07-01)

Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs
by: Bianca L. Artiaga, et al.
Published: (2022-08-01)

Human-Origin Influenza A(H3N2) Reassortant Viruses in Swine, Southeast Mexico
by: Martha I. Nelson, et al.
Published: (2019-04-01)

Determination of cold-adapted influenza virus (Orthomyxoviridae: <i>Alphainfluenzavirus</i>) polymerase activity by the minigenome method with a fluorescent protein
by: Pavel A. Ivanov, et al.
Published: (2023-12-01)

Recombinant influenza A viruses as vaccine vectors
by: Thomas Gerlach, et al.
Published: (2019-04-01)

Immunostimulating Effect of Inactivated Parapoxvirus Ovis on the Serological Response to Equine Influenza Booster Vaccination
by: Flora Carnet, et al.
Published: (2022-12-01)

Development and Evaluation of Vero Cell-Derived Master Donor Viruses for Influenza Pandemic Preparedness
by: Po-Ling Chen, et al.
Published: (2020-10-01)

A Systematic Review Analyzing the Prevalence and Circulation of Influenza Viruses in Swine Population Worldwide
by: Ravendra P. Chauhan, et al.
Published: (2020-05-01)

Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018
by: Lena Kleij, et al.
Published: (2024-03-01)

Determining Equine Influenza Virus Vaccine Efficacy—The Specific Contribution of Strain Versus Other Vaccine Attributes
by: Sylvia Reemers, et al.
Published: (2020-09-01)

Induction of Apoptosis in MDCK, RK13, and Neuro-2A Cells Infected with Equine Influenza Virus
by: Kwaśnik Małgorzata, et al.
Published: (2013-03-01)

Strain-Specific Antagonism of the Human H1N1 Influenza A Virus against Equine Tetherin
by: Meiyue Wang, et al.
Published: (2018-05-01)

Influenza A and B Virus Attachment to Respiratory Tract in Marine Mammals
by: Antonio J. Ramis, et al.
Published: (2012-05-01)