Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)

Abstract A deformable microfluidic system and a fluidic dynamic model have been successfully coupled to understand the dynamic fluid–structure interaction in transient flow, designed to understand the dentine hypersensitivity caused by hydrodynamic theory. The Polydimethylsiloxane thin sidewalls of...

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Main Authors: Chad ten Pas, Ke Du, Long Pan, Ruo-Qian Wang, Shiyou Xu
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-24112-w
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author Chad ten Pas
Ke Du
Long Pan
Ruo-Qian Wang
Shiyou Xu
author_facet Chad ten Pas
Ke Du
Long Pan
Ruo-Qian Wang
Shiyou Xu
author_sort Chad ten Pas
collection DOAJ
description Abstract A deformable microfluidic system and a fluidic dynamic model have been successfully coupled to understand the dynamic fluid–structure interaction in transient flow, designed to understand the dentine hypersensitivity caused by hydrodynamic theory. The Polydimethylsiloxane thin sidewalls of the microfluidic chip are deformed with air pressure ranging from 50 to 500 mbar to move the liquid meniscus in the central liquid channel. The experiments show that the meniscus sharply increased in the first 10th of second and the increase is nonlinearly proportional to the applied pressure. A theoretical model is developed based on the unsteady Bernoulli equation and can well predict the ending point of the liquid displacement as well as the dynamics process, regardless of the wall thickness. Moreover, an overshooting and oscillation phenomenon is observed by reducing the head loss coefficient by a few orders which could be the key to explain the dentine hypersensitivity caused by the liquid movement in the dentine tubules.
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spelling doaj.art-54ce586364e9448888894d60c11293302022-12-22T02:48:42ZengNature PortfolioScientific Reports2045-23222022-11-011211910.1038/s41598-022-24112-wUnderstanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)Chad ten Pas0Ke Du1Long Pan2Ruo-Qian Wang3Shiyou Xu4Department of Mechanical Engineering, Rochester Institute of TechnologyDepartment of Mechanical Engineering, Rochester Institute of TechnologyColgate-Palmolive Technology CenterDepartment of Civil and Environmental Engineering, Rutgers, The State University of New JerseyColgate-Palmolive Technology CenterAbstract A deformable microfluidic system and a fluidic dynamic model have been successfully coupled to understand the dynamic fluid–structure interaction in transient flow, designed to understand the dentine hypersensitivity caused by hydrodynamic theory. The Polydimethylsiloxane thin sidewalls of the microfluidic chip are deformed with air pressure ranging from 50 to 500 mbar to move the liquid meniscus in the central liquid channel. The experiments show that the meniscus sharply increased in the first 10th of second and the increase is nonlinearly proportional to the applied pressure. A theoretical model is developed based on the unsteady Bernoulli equation and can well predict the ending point of the liquid displacement as well as the dynamics process, regardless of the wall thickness. Moreover, an overshooting and oscillation phenomenon is observed by reducing the head loss coefficient by a few orders which could be the key to explain the dentine hypersensitivity caused by the liquid movement in the dentine tubules.https://doi.org/10.1038/s41598-022-24112-w
spellingShingle Chad ten Pas
Ke Du
Long Pan
Ruo-Qian Wang
Shiyou Xu
Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
Scientific Reports
title Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
title_full Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
title_fullStr Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
title_full_unstemmed Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
title_short Understanding the dynamics of fluid–structure interaction with an Air Deflected Microfluidic Chip (ADMC)
title_sort understanding the dynamics of fluid structure interaction with an air deflected microfluidic chip admc
url https://doi.org/10.1038/s41598-022-24112-w
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