Bioprinting of gelatin-based materials for orthopedic application
Bio-printed hydrogels have evolved as one of the best regenerative medicine and tissue engineering platforms due to their outstanding cell-friendly microenvironment. A correct hydrogel ink formulation is critical for creating desired scaffolds that have better fidelity after printing. Gelatin and it...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1357460/full |
| _version_ | 1797263529353412608 |
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| author | Yusuf Olatunji Waidi Ishaq Kariim Ishaq Kariim Sudipto Datta |
| author_facet | Yusuf Olatunji Waidi Ishaq Kariim Ishaq Kariim Sudipto Datta |
| author_sort | Yusuf Olatunji Waidi |
| collection | DOAJ |
| description | Bio-printed hydrogels have evolved as one of the best regenerative medicine and tissue engineering platforms due to their outstanding cell-friendly microenvironment. A correct hydrogel ink formulation is critical for creating desired scaffolds that have better fidelity after printing. Gelatin and its derivatives have sparked intense interest in various biomedical sectors because of their biocompatibility, biodegradability, ease of functionalization, and rapid gelling tendency. As a result, this report emphasizes the relevance of gelatin-based hydrogel in fabricating bio-printed scaffolds for orthopedic applications. Starting with what hydrogels and bio-printing are all about. We further summarized the different gelatin-based bio-printing techniques explored for orthopedic applications, including a few recent studies. We also discussed the suitability of gelatin as a biopolymer for both 3D and 4D printing materials. As extrusion is one of the most widely used techniques for bio-printing gelatin-based, we summarize the rheological features of gelatin-based bio-ink. Lastly, we also elaborate on the recent bio-printed gelatin-based studies for orthopedics applications, the potential clinical translation issues, and research possibilities. |
| first_indexed | 2024-04-25T00:14:27Z |
| format | Article |
| id | doaj.art-54ce94c5fc0746718912d5026422031e |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-25T00:14:27Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-54ce94c5fc0746718912d5026422031e2024-03-13T04:59:06ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852024-03-011210.3389/fbioe.2024.13574601357460Bioprinting of gelatin-based materials for orthopedic applicationYusuf Olatunji Waidi0Ishaq Kariim1Ishaq Kariim2Sudipto Datta3Indian Institute of Science (IISc), Bangalore, IndiaNelson Mandela African Institution of Science and Technology, Arusha, TanzaniaChemical Engineering Department, Federal University of Technology, Minna, NigeriaIndian Institute of Science (IISc), Bangalore, IndiaBio-printed hydrogels have evolved as one of the best regenerative medicine and tissue engineering platforms due to their outstanding cell-friendly microenvironment. A correct hydrogel ink formulation is critical for creating desired scaffolds that have better fidelity after printing. Gelatin and its derivatives have sparked intense interest in various biomedical sectors because of their biocompatibility, biodegradability, ease of functionalization, and rapid gelling tendency. As a result, this report emphasizes the relevance of gelatin-based hydrogel in fabricating bio-printed scaffolds for orthopedic applications. Starting with what hydrogels and bio-printing are all about. We further summarized the different gelatin-based bio-printing techniques explored for orthopedic applications, including a few recent studies. We also discussed the suitability of gelatin as a biopolymer for both 3D and 4D printing materials. As extrusion is one of the most widely used techniques for bio-printing gelatin-based, we summarize the rheological features of gelatin-based bio-ink. Lastly, we also elaborate on the recent bio-printed gelatin-based studies for orthopedics applications, the potential clinical translation issues, and research possibilities.https://www.frontiersin.org/articles/10.3389/fbioe.2024.1357460/fullbioprintinggelatinbioinksscaffoldsbonetissue engineering |
| spellingShingle | Yusuf Olatunji Waidi Ishaq Kariim Ishaq Kariim Sudipto Datta Bioprinting of gelatin-based materials for orthopedic application Frontiers in Bioengineering and Biotechnology bioprinting gelatin bioinks scaffolds bone tissue engineering |
| title | Bioprinting of gelatin-based materials for orthopedic application |
| title_full | Bioprinting of gelatin-based materials for orthopedic application |
| title_fullStr | Bioprinting of gelatin-based materials for orthopedic application |
| title_full_unstemmed | Bioprinting of gelatin-based materials for orthopedic application |
| title_short | Bioprinting of gelatin-based materials for orthopedic application |
| title_sort | bioprinting of gelatin based materials for orthopedic application |
| topic | bioprinting gelatin bioinks scaffolds bone tissue engineering |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2024.1357460/full |
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