Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention
Aim: The aim of this study was to investigate the relationship between no-reflow (no-RF), reflow (RF), and the P-wave time index in patients undergoing percutaneous coronary intervention (PCI) with a diagnosis of acute myocardial infarction (AMI) due to total occlusion. Methods: This study included...
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2020-01-01
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| Series: | International Journal of the Cardiovascular Academy |
| Subjects: | |
| Online Access: | http://www.ijcva.com/article.asp?issn=2405-8181;year=2020;volume=6;issue=2;spage=57;epage=65;aulast=Karakurt |
| _version_ | 1797719849316646912 |
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| author | Ahmet Karakurt Cennet Yildiz Doğan Iliş |
| author_facet | Ahmet Karakurt Cennet Yildiz Doğan Iliş |
| author_sort | Ahmet Karakurt |
| collection | DOAJ |
| description | Aim: The aim of this study was to investigate the relationship between no-reflow (no-RF), reflow (RF), and the P-wave time index in patients undergoing percutaneous coronary intervention (PCI) with a diagnosis of acute myocardial infarction (AMI) due to total occlusion. Methods: This study included a total of 272 AMI patients with no-RF (110 patients) and RF (162 patients). Results: The no-RF group had higher values of mean maxPWTpostPCI(94.95 ± 15.61 vs. 117.86 ± 12.06, P < 0.001), minPWTpostPCI(54.21 ± 12.13 vs. 67.31 ± 11.79, P < 0.001), and PWDpostPCI(39.14 ± 12.55 vs. 50.91 ± 11.9, P < 0.001) during the post-PCI period. According to multivariate logistic regression analysis, maxPWTpostPCI(odds ratio [OR]: 1.103, 95% confidence interval [CI]: 1.049–1.160, P < 0.001), minPWTpostPCI(OR: 1.055, 95% CI: 1.011–1.101, P = 0.0014), and PWDpostPCI(OR: 1.107, 95% CI: 1.037–1.181, P = 0.002) were the independent predictors of RF after PCI. ROC curve analyses demonstrated that the optimal cutoff values for maxPWTpostPCI, minPWTpostPCI, and PWDpostPCIfor predicting no-RF were 112.95 ms (area under the curve [AUC]: 0.852, 95% CI: 0.807–0.898, P < 0.001, sensitivity 70%, specificity 85.2%), 62.66 ms (AUC: 0.650, 95% CI: 0.585–0.716, P < 0.001, sensitivity 54.5%, specificity 72.8%), and 43.43 ms (AUC: 0.782, 95% CI: 0.727–0.837, P < 0.001, sensitivity 75.5%, specificity 60.5%), respectively. Conclusions: Prolonged maxPWTpostPCI, maxPWTpostPCI,and PWDpostPCIare independent predictors that differentiate no-RF from RF in patients with AMI after PCI and can be used in the follow-up of no-RF patients during the post-PCI period. |
| first_indexed | 2024-03-12T09:10:45Z |
| format | Article |
| id | doaj.art-54d06fed26604e13b695a0f9b9a72fc7 |
| institution | Directory Open Access Journal |
| issn | 2405-8181 2405-819X |
| language | English |
| last_indexed | 2024-03-12T09:10:45Z |
| publishDate | 2020-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | International Journal of the Cardiovascular Academy |
| spelling | doaj.art-54d06fed26604e13b695a0f9b9a72fc72023-09-02T14:58:11ZengGalenos Publishing HouseInternational Journal of the Cardiovascular Academy2405-81812405-819X2020-01-0162576510.4103/IJCA.IJCA_58_19Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary interventionAhmet KarakurtCennet YildizDoğan IlişAim: The aim of this study was to investigate the relationship between no-reflow (no-RF), reflow (RF), and the P-wave time index in patients undergoing percutaneous coronary intervention (PCI) with a diagnosis of acute myocardial infarction (AMI) due to total occlusion. Methods: This study included a total of 272 AMI patients with no-RF (110 patients) and RF (162 patients). Results: The no-RF group had higher values of mean maxPWTpostPCI(94.95 ± 15.61 vs. 117.86 ± 12.06, P < 0.001), minPWTpostPCI(54.21 ± 12.13 vs. 67.31 ± 11.79, P < 0.001), and PWDpostPCI(39.14 ± 12.55 vs. 50.91 ± 11.9, P < 0.001) during the post-PCI period. According to multivariate logistic regression analysis, maxPWTpostPCI(odds ratio [OR]: 1.103, 95% confidence interval [CI]: 1.049–1.160, P < 0.001), minPWTpostPCI(OR: 1.055, 95% CI: 1.011–1.101, P = 0.0014), and PWDpostPCI(OR: 1.107, 95% CI: 1.037–1.181, P = 0.002) were the independent predictors of RF after PCI. ROC curve analyses demonstrated that the optimal cutoff values for maxPWTpostPCI, minPWTpostPCI, and PWDpostPCIfor predicting no-RF were 112.95 ms (area under the curve [AUC]: 0.852, 95% CI: 0.807–0.898, P < 0.001, sensitivity 70%, specificity 85.2%), 62.66 ms (AUC: 0.650, 95% CI: 0.585–0.716, P < 0.001, sensitivity 54.5%, specificity 72.8%), and 43.43 ms (AUC: 0.782, 95% CI: 0.727–0.837, P < 0.001, sensitivity 75.5%, specificity 60.5%), respectively. Conclusions: Prolonged maxPWTpostPCI, maxPWTpostPCI,and PWDpostPCIare independent predictors that differentiate no-RF from RF in patients with AMI after PCI and can be used in the follow-up of no-RF patients during the post-PCI period.http://www.ijcva.com/article.asp?issn=2405-8181;year=2020;volume=6;issue=2;spage=57;epage=65;aulast=Karakurtacute myocardial infarctionno-reflowp-wave dispersionp-wave timereflow |
| spellingShingle | Ahmet Karakurt Cennet Yildiz Doğan Iliş Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention International Journal of the Cardiovascular Academy acute myocardial infarction no-reflow p-wave dispersion p-wave time reflow |
| title | Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| title_full | Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| title_fullStr | Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| title_full_unstemmed | Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| title_short | Effect of no-reflow/reflow on P-wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| title_sort | effect of no reflow reflow on p wave time indexes in patients with acute myocardial infarction undergoing percutaneous coronary intervention |
| topic | acute myocardial infarction no-reflow p-wave dispersion p-wave time reflow |
| url | http://www.ijcva.com/article.asp?issn=2405-8181;year=2020;volume=6;issue=2;spage=57;epage=65;aulast=Karakurt |
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