Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia
Bartonella quintana endocarditis, a common cause of culture-negative endocarditis in adults, has rarely been reported in children. We describe 5 patients 7–16 years of age from Ethiopia with heart defects and endocarditis; 4 cases were caused by infection with B. quintana and 1 by Bartonella of unde...
| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | English |
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Centers for Disease Control and Prevention
2017-08-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Acceso en liña: | https://wwwnc.cdc.gov/eid/article/23/8/16-1037_article |
| _version_ | 1828349419453415424 |
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| author | Diana Tasher Alona Raucher-Sternfeld Akiva Tamir Michael Giladi Eli Somekh |
| author_facet | Diana Tasher Alona Raucher-Sternfeld Akiva Tamir Michael Giladi Eli Somekh |
| author_sort | Diana Tasher |
| collection | DOAJ |
| description | Bartonella quintana endocarditis, a common cause of culture-negative endocarditis in adults, has rarely been reported in children. We describe 5 patients 7–16 years of age from Ethiopia with heart defects and endocarditis; 4 cases were caused by infection with B. quintana and 1 by Bartonella of undetermined species. All 5 patients were afebrile and oligosymptomatic, although 3 had heart failure. C-reactive protein was normal or slightly elevated, and erythrocyte sedimentation rate was high. The diagnosis was confirmed by echocardiographic demonstration of vegetations, the presence of high Bartonella IgG titers, and identification of B. quintana DNA in excised vegetations. Embolic events were diagnosed in 2 patients. Our data suggest that B. quintana is not an uncommon cause of native valve endocarditis in children in Ethiopia with heart defects and that possible B. quintana infection should be suspected and pursued among residents of and immigrants from East Africa, including Ethiopia, with culture-negative endocarditis. |
| first_indexed | 2024-04-14T01:10:13Z |
| format | Article |
| id | doaj.art-54d36b1b51da4a5e87d5c96d085a53f7 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-14T01:10:13Z |
| publishDate | 2017-08-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-54d36b1b51da4a5e87d5c96d085a53f72022-12-22T02:21:07ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592017-08-012381246125210.3201/eid2308.161037Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in EthiopiaDiana TasherAlona Raucher-SternfeldAkiva TamirMichael GiladiEli SomekhBartonella quintana endocarditis, a common cause of culture-negative endocarditis in adults, has rarely been reported in children. We describe 5 patients 7–16 years of age from Ethiopia with heart defects and endocarditis; 4 cases were caused by infection with B. quintana and 1 by Bartonella of undetermined species. All 5 patients were afebrile and oligosymptomatic, although 3 had heart failure. C-reactive protein was normal or slightly elevated, and erythrocyte sedimentation rate was high. The diagnosis was confirmed by echocardiographic demonstration of vegetations, the presence of high Bartonella IgG titers, and identification of B. quintana DNA in excised vegetations. Embolic events were diagnosed in 2 patients. Our data suggest that B. quintana is not an uncommon cause of native valve endocarditis in children in Ethiopia with heart defects and that possible B. quintana infection should be suspected and pursued among residents of and immigrants from East Africa, including Ethiopia, with culture-negative endocarditis.https://wwwnc.cdc.gov/eid/article/23/8/16-1037_articleBartonella quintanaBartonella spp.childreninfective endocarditisheart defectsheart failure |
| spellingShingle | Diana Tasher Alona Raucher-Sternfeld Akiva Tamir Michael Giladi Eli Somekh Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia Emerging Infectious Diseases Bartonella quintana Bartonella spp. children infective endocarditis heart defects heart failure |
| title | Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia |
| title_full | Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia |
| title_fullStr | Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia |
| title_full_unstemmed | Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia |
| title_short | Bartonella quintana, an Unrecognized Cause of Infective Endocarditis in Children in Ethiopia |
| title_sort | bartonella quintana an unrecognized cause of infective endocarditis in children in ethiopia |
| topic | Bartonella quintana Bartonella spp. children infective endocarditis heart defects heart failure |
| url | https://wwwnc.cdc.gov/eid/article/23/8/16-1037_article |
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