An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning
How glial cells like astrocytes shape complex brain functions remains unclear. Here, the authors identified an astrocyte-mediated excitatory signaling loop between neurons and their own dendritic signal integration that supports spatial memory.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-35620-8 |
| _version_ | 1797977334284812288 |
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| author | Kirsten Bohmbach Nicola Masala Eva M. Schönhense Katharina Hill André N. Haubrich Andreas Zimmer Thoralf Opitz Heinz Beck Christian Henneberger |
| author_facet | Kirsten Bohmbach Nicola Masala Eva M. Schönhense Katharina Hill André N. Haubrich Andreas Zimmer Thoralf Opitz Heinz Beck Christian Henneberger |
| author_sort | Kirsten Bohmbach |
| collection | DOAJ |
| description | How glial cells like astrocytes shape complex brain functions remains unclear. Here, the authors identified an astrocyte-mediated excitatory signaling loop between neurons and their own dendritic signal integration that supports spatial memory. |
| first_indexed | 2024-04-11T05:06:18Z |
| format | Article |
| id | doaj.art-54da0d4cedc44b3692f8f04a7d0a5037 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T05:06:18Z |
| publishDate | 2022-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-54da0d4cedc44b3692f8f04a7d0a50372022-12-25T12:21:40ZengNature PortfolioNature Communications2041-17232022-12-0113111710.1038/s41467-022-35620-8An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learningKirsten Bohmbach0Nicola Masala1Eva M. Schönhense2Katharina Hill3André N. Haubrich4Andreas Zimmer5Thoralf Opitz6Heinz Beck7Christian Henneberger8Institute of Cellular Neurosciences, Medical Faculty, University of BonnInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of BonnInstitute of Cellular Neurosciences, Medical Faculty, University of BonnInstitute of Cellular Neurosciences, Medical Faculty, University of BonnInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of BonnInstitute of Molecular Psychiatry, Medical Faculty, University of BonnInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of BonnInstitute of Experimental Epileptology and Cognition Research, Medical Faculty, University of BonnInstitute of Cellular Neurosciences, Medical Faculty, University of BonnHow glial cells like astrocytes shape complex brain functions remains unclear. Here, the authors identified an astrocyte-mediated excitatory signaling loop between neurons and their own dendritic signal integration that supports spatial memory.https://doi.org/10.1038/s41467-022-35620-8 |
| spellingShingle | Kirsten Bohmbach Nicola Masala Eva M. Schönhense Katharina Hill André N. Haubrich Andreas Zimmer Thoralf Opitz Heinz Beck Christian Henneberger An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning Nature Communications |
| title | An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning |
| title_full | An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning |
| title_fullStr | An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning |
| title_full_unstemmed | An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning |
| title_short | An astrocytic signaling loop for frequency-dependent control of dendritic integration and spatial learning |
| title_sort | astrocytic signaling loop for frequency dependent control of dendritic integration and spatial learning |
| url | https://doi.org/10.1038/s41467-022-35620-8 |
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