Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms
Background: If asthmatic children cannot obtain sufficient control of their disease, not only do they suffer from asthma symptoms, but the daily life activities of their caregivers are also disrupted. We investigated the effectiveness of an inhaled corticosteroid (ICS) for symptom control in previou...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-10-01
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| Series: | Allergology International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1323893015001227 |
| _version_ | 1811267804464152576 |
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| author | Shigemi Yoshihara Noriko Kanno Hironobu Fukuda Osamu Arisaka Masahiko Arita Kunio Sekine Koichi Yamaguchi Akira Tsuchida Yumi Yamada Toru Watanabe Toshio Shimizu Kiyoshi Nishikawa Toshiyuki Nishimuta |
| author_facet | Shigemi Yoshihara Noriko Kanno Hironobu Fukuda Osamu Arisaka Masahiko Arita Kunio Sekine Koichi Yamaguchi Akira Tsuchida Yumi Yamada Toru Watanabe Toshio Shimizu Kiyoshi Nishikawa Toshiyuki Nishimuta |
| author_sort | Shigemi Yoshihara |
| collection | DOAJ |
| description | Background: If asthmatic children cannot obtain sufficient control of their disease, not only do they suffer from asthma symptoms, but the daily life activities of their caregivers are also disrupted. We investigated the effectiveness of an inhaled corticosteroid (ICS) for symptom control in previously ICS-untreated school-aged asthmatic children as well as caregiver treatment satisfaction (CTS).
Methods: A multicenter, open-label, single-arm study on 12-week ICS (budesonide Turbuhaler®) monotherapy was undertaken in subjects aged 5–15 years with bronchial asthma not treated with ICS during the previous 3 months. At 0, 4, 8, and 12 weeks after start of ICS administration, Japanese Pediatric Asthma Control Program (JPAC) scores, and CTS scores were summated and lung function measured. At weeks 0 and 12, questionnaires on caregiver anxiety were also assessed.
Results: Seventy-five patients were enrolled, and 69 assessed. Ninety percent of subjects had been treated with asthma controller medication except ICS before study enrollment. JPAC score and CTS score were improved significantly at weeks 4, 8, and 12 (p < 0.001). With regard to CTS, more than half of caregivers showed a perfect score at weeks 8 and 12. There was a significant correlation between JPAC score and CTS score. Lung function and caregiver anxiety were also improved, and good compliance with treatment was observed during the intervention.
Conclusions: If treating ICS-untreated school-aged asthmatic children with uncontrolled symptoms, ICS monotherapy can improve CTS along with improving asthma control. |
| first_indexed | 2024-04-12T21:09:22Z |
| format | Article |
| id | doaj.art-54dff9933b3c4463bbb72812748151a4 |
| institution | Directory Open Access Journal |
| issn | 1323-8930 |
| language | English |
| last_indexed | 2024-04-12T21:09:22Z |
| publishDate | 2015-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Allergology International |
| spelling | doaj.art-54dff9933b3c4463bbb72812748151a42022-12-22T03:16:37ZengElsevierAllergology International1323-89302015-10-0164437137610.1016/j.alit.2015.05.010Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptomsShigemi Yoshihara0Noriko Kanno1Hironobu Fukuda2Osamu Arisaka3Masahiko Arita4Kunio Sekine5Koichi Yamaguchi6Akira Tsuchida7Yumi Yamada8Toru Watanabe9Toshio Shimizu10Kiyoshi Nishikawa11Toshiyuki Nishimuta12Department of Pediatrics, Dokkyo Medical University, Tochigi, JapanDepartment of Pediatrics, Dokkyo Medical University, Tochigi, JapanDepartment of Pediatrics, Dokkyo Medical University, Tochigi, JapanDepartment of Pediatrics, Dokkyo Medical University, Tochigi, JapanArita Clinic of Pediatrics and Pediatric Allergy, Hiroshima, JapanSekine Pediatric Clinic, Chiba, JapanDepartment of Pediatrics, The Fraternity Memorial Hospital, Tokyo, JapanTsuchida Kodomo Clinic, Kanagawa, JapanYamada Gastrointestinal Internal Medicine and Pediatric Clinic, Tochigi, JapanWatanabe Pediatric Allergy Clinic, Hokkaido, JapanShimizu Pediatrics and Allergy Clinic, Saitama, JapanNishikawa Clinic, Kagawa, JapanDepartment of Pediatrics, National Hospital Organization Shimoshizu National Hospital, Chiba, JapanBackground: If asthmatic children cannot obtain sufficient control of their disease, not only do they suffer from asthma symptoms, but the daily life activities of their caregivers are also disrupted. We investigated the effectiveness of an inhaled corticosteroid (ICS) for symptom control in previously ICS-untreated school-aged asthmatic children as well as caregiver treatment satisfaction (CTS). Methods: A multicenter, open-label, single-arm study on 12-week ICS (budesonide Turbuhaler®) monotherapy was undertaken in subjects aged 5–15 years with bronchial asthma not treated with ICS during the previous 3 months. At 0, 4, 8, and 12 weeks after start of ICS administration, Japanese Pediatric Asthma Control Program (JPAC) scores, and CTS scores were summated and lung function measured. At weeks 0 and 12, questionnaires on caregiver anxiety were also assessed. Results: Seventy-five patients were enrolled, and 69 assessed. Ninety percent of subjects had been treated with asthma controller medication except ICS before study enrollment. JPAC score and CTS score were improved significantly at weeks 4, 8, and 12 (p < 0.001). With regard to CTS, more than half of caregivers showed a perfect score at weeks 8 and 12. There was a significant correlation between JPAC score and CTS score. Lung function and caregiver anxiety were also improved, and good compliance with treatment was observed during the intervention. Conclusions: If treating ICS-untreated school-aged asthmatic children with uncontrolled symptoms, ICS monotherapy can improve CTS along with improving asthma control.http://www.sciencedirect.com/science/article/pii/S1323893015001227Asthma symptomsBudesonide monotherapyCaregiver treatment satisfactionJPACPediatric asthma |
| spellingShingle | Shigemi Yoshihara Noriko Kanno Hironobu Fukuda Osamu Arisaka Masahiko Arita Kunio Sekine Koichi Yamaguchi Akira Tsuchida Yumi Yamada Toru Watanabe Toshio Shimizu Kiyoshi Nishikawa Toshiyuki Nishimuta Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms Allergology International Asthma symptoms Budesonide monotherapy Caregiver treatment satisfaction JPAC Pediatric asthma |
| title | Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms |
| title_full | Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms |
| title_fullStr | Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms |
| title_full_unstemmed | Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms |
| title_short | Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms |
| title_sort | caregiver treatment satisfaction is improved together with children s asthma control prospective study for budesonide monotherapy in school aged children with uncontrolled asthma symptoms |
| topic | Asthma symptoms Budesonide monotherapy Caregiver treatment satisfaction JPAC Pediatric asthma |
| url | http://www.sciencedirect.com/science/article/pii/S1323893015001227 |
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