Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography
Abstract In this paper, a nano-porous polymer has been integrated into the microfluidics device as on-chip monolithic liquid chromatography column for separation of chemical and biological samples. Monolithic nano-porous polymer (MNP) was formed and firmly grafted on the surface of the microfluidic...
Main Authors: | , |
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Format: | Article |
Language: | English |
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SpringerOpen
2018-07-01
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Series: | Nano Convergence |
Online Access: | http://link.springer.com/article/10.1186/s40580-018-0151-4 |
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author | Jin-young Kim Danny O’Hare |
author_facet | Jin-young Kim Danny O’Hare |
author_sort | Jin-young Kim |
collection | DOAJ |
description | Abstract In this paper, a nano-porous polymer has been integrated into the microfluidics device as on-chip monolithic liquid chromatography column for separation of chemical and biological samples. Monolithic nano-porous polymer (MNP) was formed and firmly grafted on the surface of the microfluidic channel. Neurotransmitters, 5-hydroxyindole-3-acetic acid (5-HIAA) and 5-hydroxytryptamine (serotonin, 5-HT), were successfully separated with the developed on-chip MNP column. |
first_indexed | 2024-12-13T07:54:06Z |
format | Article |
id | doaj.art-54e00b914c92492aa6553e17cdb0c5c1 |
institution | Directory Open Access Journal |
issn | 2196-5404 |
language | English |
last_indexed | 2024-12-13T07:54:06Z |
publishDate | 2018-07-01 |
publisher | SpringerOpen |
record_format | Article |
series | Nano Convergence |
spelling | doaj.art-54e00b914c92492aa6553e17cdb0c5c12022-12-21T23:54:34ZengSpringerOpenNano Convergence2196-54042018-07-01511710.1186/s40580-018-0151-4Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatographyJin-young Kim0Danny O’Hare1DGIST-ETH Microrobotics Research Center, DGISTDepartment of Bioengineering, Imperial College LondonAbstract In this paper, a nano-porous polymer has been integrated into the microfluidics device as on-chip monolithic liquid chromatography column for separation of chemical and biological samples. Monolithic nano-porous polymer (MNP) was formed and firmly grafted on the surface of the microfluidic channel. Neurotransmitters, 5-hydroxyindole-3-acetic acid (5-HIAA) and 5-hydroxytryptamine (serotonin, 5-HT), were successfully separated with the developed on-chip MNP column.http://link.springer.com/article/10.1186/s40580-018-0151-4 |
spellingShingle | Jin-young Kim Danny O’Hare Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography Nano Convergence |
title | Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography |
title_full | Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography |
title_fullStr | Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography |
title_full_unstemmed | Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography |
title_short | Monolithic nano-porous polymer in microfluidic channels for lab-chip liquid chromatography |
title_sort | monolithic nano porous polymer in microfluidic channels for lab chip liquid chromatography |
url | http://link.springer.com/article/10.1186/s40580-018-0151-4 |
work_keys_str_mv | AT jinyoungkim monolithicnanoporouspolymerinmicrofluidicchannelsforlabchipliquidchromatography AT dannyohare monolithicnanoporouspolymerinmicrofluidicchannelsforlabchipliquidchromatography |