Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review
Coffee is an important dietary source of biologically active components, not to mention caffeine, phenolic acids, and diterpenes. It has been suggested that selected coffee secondary metabolites may beneficially modulate several mechanisms of anti-cancer protection. This literature review was intend...
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| Format: | Article |
| Language: | English |
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Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences
2020-05-01
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| Series: | Polish Journal of Food and Nutrition Sciences |
| Subjects: | |
| Online Access: | http://www.journalssystem.com/pjfns/Coffee-and-its-biologically-active-components-is-there-a-connection-to-breast-endometrial,120017,0,2.html |
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| author | Anna Maria Witkowska Iwona Mirończuk-Chodakowska Katarzyna Maria Terlikowska Kamila Kulesza Małgorzata Elżbieta Zujko |
| author_facet | Anna Maria Witkowska Iwona Mirończuk-Chodakowska Katarzyna Maria Terlikowska Kamila Kulesza Małgorzata Elżbieta Zujko |
| author_sort | Anna Maria Witkowska |
| collection | DOAJ |
| description | Coffee is an important dietary source of biologically active components, not to mention caffeine, phenolic acids, and diterpenes. It has been suggested that selected coffee secondary metabolites may beneficially modulate several mechanisms of anti-cancer protection. This literature review was intended to present current knowledge related to coffee and its components and hormone-dependent female cancers, such as breast, endometrial and ovarian cancer, and to identify gaps in research that may be exploited in the future. The search for studies was conducted through electronic databases. Publications on coffee composition, coffee preparation and brewing methods, in vitro and in vivo experiments with the use of substances naturally present in coffee, observational studies, and meta-analyses were collected. In population studies, the greatest attention has been paid to the anticancer effect of caffeinated coffee and/or caffeine. In general, most studies and meta-analyses indicated that there was no clear correlation between coffee and breast cancer or ovarian cancer. Some subgroups of women may benefit from coffee consumption. This is the case for post-menopausal women with regard to the risk of breast cancer and obese women with regard to the risk of endometrial cancer. This paper identifies a number of issues for future research, related to a better understanding of the anti-cancer mechanisms of coffee compounds and further research that would focus on specific target groups, taking into account both the different methods of coffee preparation and lifestyle factors that may influence the results. |
| first_indexed | 2024-12-21T17:33:28Z |
| format | Article |
| id | doaj.art-54e176e46477402b82ecc254cf785da4 |
| institution | Directory Open Access Journal |
| issn | 2083-6007 |
| language | English |
| last_indexed | 2025-02-16T12:52:59Z |
| publishDate | 2020-05-01 |
| publisher | Institute of Animal Reproduction and Food Research of the Polish Academy of Sciences |
| record_format | Article |
| series | Polish Journal of Food and Nutrition Sciences |
| spelling | doaj.art-54e176e46477402b82ecc254cf785da42025-02-02T19:52:34ZengInstitute of Animal Reproduction and Food Research of the Polish Academy of SciencesPolish Journal of Food and Nutrition Sciences2083-60072020-05-0170320722210.31883/pjfns/120017120017Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a ReviewAnna Maria Witkowska0Iwona Mirończuk-Chodakowska1Katarzyna Maria Terlikowska2Kamila Kulesza3Małgorzata Elżbieta Zujko4Department of Food Biotechnology, Faculty of Health Sciences, Medical University, Szpitalna 37, 15-295 Białystok, PolandDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University, Szpitalna 37, 15-295 Białystok, PolandDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University, Szpitalna 37, 15-295 Białystok, PolandDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University, Szpitalna 37, 15-295 Białystok, PolandDepartment of Food Biotechnology, Faculty of Health Sciences, Medical University, Szpitalna 37, 15-295 Białystok, PolandCoffee is an important dietary source of biologically active components, not to mention caffeine, phenolic acids, and diterpenes. It has been suggested that selected coffee secondary metabolites may beneficially modulate several mechanisms of anti-cancer protection. This literature review was intended to present current knowledge related to coffee and its components and hormone-dependent female cancers, such as breast, endometrial and ovarian cancer, and to identify gaps in research that may be exploited in the future. The search for studies was conducted through electronic databases. Publications on coffee composition, coffee preparation and brewing methods, in vitro and in vivo experiments with the use of substances naturally present in coffee, observational studies, and meta-analyses were collected. In population studies, the greatest attention has been paid to the anticancer effect of caffeinated coffee and/or caffeine. In general, most studies and meta-analyses indicated that there was no clear correlation between coffee and breast cancer or ovarian cancer. Some subgroups of women may benefit from coffee consumption. This is the case for post-menopausal women with regard to the risk of breast cancer and obese women with regard to the risk of endometrial cancer. This paper identifies a number of issues for future research, related to a better understanding of the anti-cancer mechanisms of coffee compounds and further research that would focus on specific target groups, taking into account both the different methods of coffee preparation and lifestyle factors that may influence the results.http://www.journalssystem.com/pjfns/Coffee-and-its-biologically-active-components-is-there-a-connection-to-breast-endometrial,120017,0,2.htmlcoffeecaffeinebreast cancerovarian cancerendometrial cancer |
| spellingShingle | Anna Maria Witkowska Iwona Mirończuk-Chodakowska Katarzyna Maria Terlikowska Kamila Kulesza Małgorzata Elżbieta Zujko Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review Polish Journal of Food and Nutrition Sciences coffee caffeine breast cancer ovarian cancer endometrial cancer |
| title | Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review |
| title_full | Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review |
| title_fullStr | Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review |
| title_full_unstemmed | Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review |
| title_short | Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review |
| title_sort | coffee and its biologically active components is there a connection to breast endometrial and ovarian cancer a review |
| topic | coffee caffeine breast cancer ovarian cancer endometrial cancer |
| url | http://www.journalssystem.com/pjfns/Coffee-and-its-biologically-active-components-is-there-a-connection-to-breast-endometrial,120017,0,2.html |
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