Predominant transmission of KPC-2 carbapenemase in Germany by a unique IncN plasmid variant harboring a novel non-transposable element (NTE KPC -Y)

Predominant transmission of KPC-2 carbapenemase in Germany by a unique IncN plasmid variant harboring a novel non-transposable element (NTE KPC -Y)

ABSTRACT Carbapenemase-producing Enterobacterales (CPE) pose a major public health threat. Despite active infection prevention efforts, the incidence of KPC-2 carbapenemase-producing Enterobacterales (KPC2-CPE) continues to increase worldwide. In this study, we performed genome sequencing of 135 KPC...

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Bibliographic Details
Main Authors: Yancheng Yao, Linda Falgenhauer, Yalda Rezazadeh, Jane Falgenhauer, Can Imirzalioglu, Trinad Chakraborty
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:Microbiology Spectrum
Subjects:
KPC-2
IncN
plasmid-mediated transmission
non-Tn4401-element
carbapenem resistance
Enterobacterales
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02564-23

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