Omega-3 fatty acids upregulate Nrf2 expression and attenuate apoptosis, inflammation, and fibrosis in a rat model of cyclosporine-induced nephropathy

Omega-3 fatty acids upregulate Nrf2 expression and attenuate apoptosis, inflammation, and fibrosis in a rat model of cyclosporine-induced nephropathy

Background Cyclosporine A (CsA)-induced kidney injury is characterized by renal impairment with inflammatory cell infiltrations, apoptosis, fibrosis, and hypoxic injury. It is not clear whether omega-3 fatty acids (O-3 FAs), which have anti-inflammatory and antioxidant roles, affect nuclear factor e...

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Bibliographic Details
Main Authors: Ji Young Lee, Young Ki Son, Mi Hwa Lee, Su Mi Lee, Seong Eun Kim, Won Suk An
Format: Article
Language:English
Published: Kosin University College of Medicine 2023-09-01
Series:Kosin Medical Journal
Subjects:
apoptosis
fibrosis
inflammation
nuclear factor erythroid 2-related factor 2
omega-3 fatty acid
Online Access:http://www.kosinmedj.org/upload/pdf/kmj-23-112.pdf

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