Antimicrobial activity and pathogen mutation prevention of originator and generics of cefepime, linezolid and piperacillin/tazobactam against clinical isolates of Staphylococcus aureus

Antimicrobial activity and pathogen mutation prevention of originator and generics of cefepime, linezolid and piperacillin/tazobactam against clinical isolates of Staphylococcus aureus

ABSTRACT: Objectives: Although generic medicinal products are required to have the same qualitative and quantitative composition of the active substance as their reference originator product, patients and health care professionals express concerns about their interchangeability and safety. Therefor...

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Bibliographic Details
Main Authors: Felix Bergmann, Alina Nussbaumer-Pröll, Beatrix Wulkersdorfer, Sabine Eberl, Werner Ruppitsch, Sarah Lepuschitz, Markus Zeitlinger
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Antibiotics
MIC
MPC
Bioequivalence
S. aureus
Genome
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716523001121

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