Combined thrombogenic effects of vessel injury, pregnancy and procoagulant immune globulin administration in mice

Combined thrombogenic effects of vessel injury, pregnancy and procoagulant immune globulin administration in mice

Abstract Background Pregnant women are at increased risk of thrombotic adverse events. Plasma derived immune globulin (IG) products, which are used in pregnancy for various indications, may contain procoagulant impurity activated coagulation factor XI (FXIa). Procoagulant IG products have been assoc...

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Bibliographic Details
Main Authors: Yanqun Xu, Yideng Liang, Leonid Parunov, Daryl Despres, Michael Eckhaus, Dorothy Scott, Mikhail Ovanesov, Evi B. Struble
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Thrombosis Journal
Subjects:
Factor XIa
FXIa
Thrombogenicity
Immune globulin
Thrombosis
Online Access:http://link.springer.com/article/10.1186/s12959-020-00245-8

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