Effect of hypothyroidism on lipid profile in women at Misan City/Iraq
Background: Hypothyroidism is a common endocrine disorder resulting from insufficient production of thyroid hormones, which have significant effects on the synthesis, mobilization, and metabolism of lipids. Objective: The present study aimed to measure some hormonal and biochemical parameters in wom...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2020-01-01
|
| Series: | Medical Journal of Babylon |
| Subjects: | |
| Online Access: | http://www.medjbabylon.org/article.asp?issn=1812-156X;year=2020;volume=17;issue=1;spage=1;epage=5;aulast=Aati |
| Summary: | Background: Hypothyroidism is a common endocrine disorder resulting from insufficient production of thyroid hormones, which have significant effects on the synthesis, mobilization, and metabolism of lipids. Objective: The present study aimed to measure some hormonal and biochemical parameters in women suffering from hypothyroidism in Misan province. Materials and Methods: This study included 88 women aged 20–35 years. 5–7 ml of blood was drawn, and serum was obtained. Thyroid and lipid profile tests were performed on all women. Results: The values of thyroid-stimulating hormone increased statistically significantly (P < 0.05) in the C (hypothyroidism women) and D (hypothyroidism and infertility women) groups, whereas triiodothyronine and thyroxin results decreased statistically significantly (P < 0.05) in the C (hypothyroidism women) and D (hypothyroidism and infertility women) groups. Triglycerides and very low-density lipoprotein (LDL)-cholesterol increased statistically significantly (P < 0.05) in the B (infertility women) and C (hypothyroidism women) groups compared to A (healthy women) and D (hypothyroidism and infertility women) groups, whereas LDL cholesterol (LDL-C increased statistically significantly (P < 0.05) in C (hypothyroidism women) and D (hypothyroidism and infertility women) groups compared with A (healthy women) and B (infertility women) groups. There were no statistically significant differences (P < 0.05) in total cholesterol and high-density lipoprotein-cholesterol among the study groups. Conclusions: Hypothyroidism causes increasing level of LDL. Indeed, it is a common cause of secondary dyslipidemia. |
|---|---|
| ISSN: | 1812-156X 2312-6760 |