Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context
Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biological aging process in humans remains limited. Met...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | The Lancet Regional Health. Western Pacific |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666606523002730 |
| _version_ | 1797506303874039808 |
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| author | Yi Xiang Hao Xu Hongxiang Chen Dan Tang Zitong Huang Yuan Zhang Zhenghong Wang Ziyun Wang Yangla Mingming Han Jianzhong Yin Xiong Xiao Xing Zhao |
| author_facet | Yi Xiang Hao Xu Hongxiang Chen Dan Tang Zitong Huang Yuan Zhang Zhenghong Wang Ziyun Wang Yangla Mingming Han Jianzhong Yin Xiong Xiao Xing Zhao |
| author_sort | Yi Xiang |
| collection | DOAJ |
| description | Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biological aging process in humans remains limited. Methods: This study included 7931 participants aged 30–79 years from the China Multi-Ethnic Cohort (CMEC) Study and 5998 participants aged 37–73 years from the UK Biobank (UKB) who participated in both the baseline and first follow-up surveys. Tea consumption information was collected through questionnaires. Biological age (BA) acceleration was calculated using clinical biomarkers and anthropometric measurements based on the Klemera Doubal method (KDM). Change-to-change analyses were performed to estimate the associations between changes in tea consumption status and changes in BA acceleration using multiple linear models. Follow-up adjusted for baseline analyses were further conducted to examine the prospective exposure-response relationship between tea consumption and BA acceleration among individuals with constant tea consumption status. Findings: During a median follow-up of 1.98 (1.78, 2.16) years in the CMEC and 4.50 (3.92, 5.00) years in the UKB, tea consumption was consistently associated with attenuated BA acceleration in both cohorts. Transitioning from nondrinking to tea-drinking was associated with decreased BA acceleration (CMEC: β = −0.319, 95% CI: −0.620 to −0.017 years; UKB: β = −0.267, 95% CI: −0.831 to 0.297 years) compared to consistent nondrinking. Even stronger associations were found in consistent tea drinkers. The exposure-response relationship suggested that consuming around 3 cups of tea or 6–8 g of tea leaves per day may offer the most evident anti-aging benefits. Interpretation: Tea consumption was associated with attenuated BA acceleration measured by KDM, especially for consistent tea drinkers with moderate consumption. Our findings highlight the potential role of tea in developing nutrition-oriented anti-aging interventions and guiding healthy aging policies. Funding: National Natural Science Foundation of China (Grant No. 82273740). |
| first_indexed | 2024-03-10T04:30:44Z |
| format | Article |
| id | doaj.art-54e9d5d99e2d4bc9a80aa4c4e5f19094 |
| institution | Directory Open Access Journal |
| issn | 2666-6065 |
| language | English |
| last_indexed | 2024-03-10T04:30:44Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Lancet Regional Health. Western Pacific |
| spelling | doaj.art-54e9d5d99e2d4bc9a80aa4c4e5f190942023-11-23T04:29:11ZengElsevierThe Lancet Regional Health. Western Pacific2666-60652024-01-0142100955Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in contextYi Xiang0Hao Xu1Hongxiang Chen2Dan Tang3Zitong Huang4Yuan Zhang5Zhenghong Wang6Ziyun Wang7 Yangla8Mingming Han9Jianzhong Yin10Xiong Xiao11Xing Zhao12West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaState Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, ChinaWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, ChinaChongqing Municipal Center for Disease Control and Prevention, Chongqing, ChinaSchool of Public Health, The Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, ChinaHigh Altitude Health Science Research Center of Tibet University, Lhasa, ChinaChengdu Center for Disease Control and Prevention, Chengdu, ChinaSchool of Public Health, Kunming Medical University, Kunming, China; Baoshan College of Traditional Chinese Medicine, Baoshan, ChinaWest China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China; Corresponding authors. Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan CN 610041, China.West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China; Corresponding authors. Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan CN 610041, China.Summary: Background: The biological aging process can be modified through lifestyle interventions to prevent age-related diseases and extend healthspan. However, evidence from population-based studies on whether tea consumption could delay the biological aging process in humans remains limited. Methods: This study included 7931 participants aged 30–79 years from the China Multi-Ethnic Cohort (CMEC) Study and 5998 participants aged 37–73 years from the UK Biobank (UKB) who participated in both the baseline and first follow-up surveys. Tea consumption information was collected through questionnaires. Biological age (BA) acceleration was calculated using clinical biomarkers and anthropometric measurements based on the Klemera Doubal method (KDM). Change-to-change analyses were performed to estimate the associations between changes in tea consumption status and changes in BA acceleration using multiple linear models. Follow-up adjusted for baseline analyses were further conducted to examine the prospective exposure-response relationship between tea consumption and BA acceleration among individuals with constant tea consumption status. Findings: During a median follow-up of 1.98 (1.78, 2.16) years in the CMEC and 4.50 (3.92, 5.00) years in the UKB, tea consumption was consistently associated with attenuated BA acceleration in both cohorts. Transitioning from nondrinking to tea-drinking was associated with decreased BA acceleration (CMEC: β = −0.319, 95% CI: −0.620 to −0.017 years; UKB: β = −0.267, 95% CI: −0.831 to 0.297 years) compared to consistent nondrinking. Even stronger associations were found in consistent tea drinkers. The exposure-response relationship suggested that consuming around 3 cups of tea or 6–8 g of tea leaves per day may offer the most evident anti-aging benefits. Interpretation: Tea consumption was associated with attenuated BA acceleration measured by KDM, especially for consistent tea drinkers with moderate consumption. Our findings highlight the potential role of tea in developing nutrition-oriented anti-aging interventions and guiding healthy aging policies. Funding: National Natural Science Foundation of China (Grant No. 82273740).http://www.sciencedirect.com/science/article/pii/S2666606523002730Biological agingTea consumptionChange-to-change analysisFollow-up adjusted for baseline analysisExposure-response relationship |
| spellingShingle | Yi Xiang Hao Xu Hongxiang Chen Dan Tang Zitong Huang Yuan Zhang Zhenghong Wang Ziyun Wang Yangla Mingming Han Jianzhong Yin Xiong Xiao Xing Zhao Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context The Lancet Regional Health. Western Pacific Biological aging Tea consumption Change-to-change analysis Follow-up adjusted for baseline analysis Exposure-response relationship |
| title | Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
| title_full | Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
| title_fullStr | Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
| title_full_unstemmed | Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
| title_short | Tea consumption and attenuation of biological aging: a longitudinal analysis from two cohort studiesResearch in context |
| title_sort | tea consumption and attenuation of biological aging a longitudinal analysis from two cohort studiesresearch in context |
| topic | Biological aging Tea consumption Change-to-change analysis Follow-up adjusted for baseline analysis Exposure-response relationship |
| url | http://www.sciencedirect.com/science/article/pii/S2666606523002730 |
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