Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract

Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed mat...

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Main Authors: Magdalena Kędzierska, Katarzyna Sala, Magdalena Bańkosz, Dominika Wroniak, Paweł Gajda, Piotr Potemski, Bożena Tyliszczak
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Materials
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Online Access:https://www.mdpi.com/1996-1944/16/17/6037
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author Magdalena Kędzierska
Katarzyna Sala
Magdalena Bańkosz
Dominika Wroniak
Paweł Gajda
Piotr Potemski
Bożena Tyliszczak
author_facet Magdalena Kędzierska
Katarzyna Sala
Magdalena Bańkosz
Dominika Wroniak
Paweł Gajda
Piotr Potemski
Bożena Tyliszczak
author_sort Magdalena Kędzierska
collection DOAJ
description Hydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications.
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spelling doaj.art-54ec0c39aaf347449f4ef43edbd337292023-11-19T08:29:23ZengMDPI AGMaterials1996-19442023-09-011617603710.3390/ma16176037Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip ExtractMagdalena Kędzierska0Katarzyna Sala1Magdalena Bańkosz2Dominika Wroniak3Paweł Gajda4Piotr Potemski5Bożena Tyliszczak6Department of Chemotherapy, Medical University of Lodz, Copernicus Memorial Hospital of Lodz, 90-549 Lodz, PolandDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, PolandDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, PolandDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, PolandDepartment of Sustainable Energy Development, Faculty of Energy and Fuels, AGH University of Science and Technology, 30 Mickiewicza Av., 30-059 Krakow, PolandDepartment of Chemotherapy, Medical University of Lodz, Copernicus Memorial Hospital of Lodz, 90-549 Lodz, PolandDepartment of Materials Engineering, Faculty of Materials Engineering and Physics, Cracow University of Technology, 37 Jana Pawła II Av., 31-864 Krakow, PolandHydrogel materials are used in many fields of science and industry. They are of particular importance in biomedical applications. In this work, hydrogels were obtained that could act as a dressing for wounds, at the same time being a carrier of substances with antioxidant activity. The discussed materials were obtained in the field of UV radiation. The correlation between the amount of photoinitiator used and the physicochemical properties and surface morphology of the obtained materials was investigated. In addition, the hydrogels have been incorporated with wild rose extract, which is characterized by antioxidant and anti-inflammatory effects. The analysis of the sorption capacity confirmed that the obtained material is able to absorb significant amounts of incubation fluids, which, in terms of application, will enable the absorption of exudate from the wound. The highest stability of materials was noted for hydrogels obtained with the use of intermediate amounts of photoinitiator, i.e., 50 µL and 70 µL. In the case of using 20 µL or 100 µL, the photopolymerization process did not proceed properly and the obtained material was characterized by a lack of homogeneity and high brittleness. With the increase in the amount of photoinitiator, an increase in the surface roughness of hydrogel materials was confirmed. In turn, spectroscopic analysis ruled out the degradation of materials in incubation fluids, indicating the potential for their use in biomedical applications.https://www.mdpi.com/1996-1944/16/17/6037hydrogelsrosehip extractroughnesssorption capacity
spellingShingle Magdalena Kędzierska
Katarzyna Sala
Magdalena Bańkosz
Dominika Wroniak
Paweł Gajda
Piotr Potemski
Bożena Tyliszczak
Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
Materials
hydrogels
rosehip extract
roughness
sorption capacity
title Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_full Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_fullStr Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_full_unstemmed Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_short Investigation of Physicochemical Properties and Surface Morphology of Hydrogel Materials Incorporating Rosehip Extract
title_sort investigation of physicochemical properties and surface morphology of hydrogel materials incorporating rosehip extract
topic hydrogels
rosehip extract
roughness
sorption capacity
url https://www.mdpi.com/1996-1944/16/17/6037
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AT katarzynasala investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract
AT magdalenabankosz investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract
AT dominikawroniak investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract
AT pawełgajda investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract
AT piotrpotemski investigationofphysicochemicalpropertiesandsurfacemorphologyofhydrogelmaterialsincorporatingrosehipextract
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