Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report

Nicolau syndrome is a rare drug reaction due to intramuscular injection administration that can lead to limb loss or even death. A 3.8- year-old Iranian boy received an intramuscular injection of Benzathine Penicillin. Immediately after injection the child developed lower limb pain and livedoid di...

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Main Authors: Masoud Hatefi, Nabi Ramezani Pirabadi, Javaher Khajavikhan, Molouk Jaafarpour
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-10-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/6596/14833_CE(RA1)_F(T)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf
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author Masoud Hatefi
Nabi Ramezani Pirabadi
Javaher Khajavikhan
Molouk Jaafarpour
author_facet Masoud Hatefi
Nabi Ramezani Pirabadi
Javaher Khajavikhan
Molouk Jaafarpour
author_sort Masoud Hatefi
collection DOAJ
description Nicolau syndrome is a rare drug reaction due to intramuscular injection administration that can lead to limb loss or even death. A 3.8- year-old Iranian boy received an intramuscular injection of Benzathine Penicillin. Immediately after injection the child developed lower limb pain and livedoid discolouration and was referred to our department. The patient was diagnosed to develop Nicolau syndrome and fasciotomy carried out due to compartment syndrome. Pharmacologic therapy with Heparin, Cefazolin and Methylprednisolone was initiated. On 18th day, he was discharged, although he was not able to move. Finally, after 6 months of care at home, physiotherapy and Electromyography (EMG) at regular intervals, the child was gradually able to move and his claudication improved.
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spelling doaj.art-54ec9a3ed01a4684bde67c704eacd34a2022-12-21T18:13:45ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-10-01910RD01RD0210.7860/JCDR/2015/14833.6596Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case ReportMasoud Hatefi0Nabi Ramezani Pirabadi1Javaher Khajavikhan2Molouk Jaafarpour3Neurosurgeon, Department of Neurosurgery, Medicine Faculty, Ilam University of Medical Science, Ilam, IR-Iran. Orthopaedist, Department of Orthopaedics, Medicine Faculty, Ilam University of Medical Science, Ilam, IR-Iran. Anaesthesiologist, Department of Anesthesiology, Medicine Faculty, Ilam University of Medical Science, Ilam, IR-Iran.MSc of Midwifery, Department of Midwifery, Nursing & Midwifery Faculty, Ilam University of Medical Science, Ilam, IR-Iran.Nicolau syndrome is a rare drug reaction due to intramuscular injection administration that can lead to limb loss or even death. A 3.8- year-old Iranian boy received an intramuscular injection of Benzathine Penicillin. Immediately after injection the child developed lower limb pain and livedoid discolouration and was referred to our department. The patient was diagnosed to develop Nicolau syndrome and fasciotomy carried out due to compartment syndrome. Pharmacologic therapy with Heparin, Cefazolin and Methylprednisolone was initiated. On 18th day, he was discharged, although he was not able to move. Finally, after 6 months of care at home, physiotherapy and Electromyography (EMG) at regular intervals, the child was gradually able to move and his claudication improved.https://jcdr.net/articles/PDF/6596/14833_CE(RA1)_F(T)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdfbenzathine penicillincompartment syndromechilddrug reaction
spellingShingle Masoud Hatefi
Nabi Ramezani Pirabadi
Javaher Khajavikhan
Molouk Jaafarpour
Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
Journal of Clinical and Diagnostic Research
benzathine penicillin
compartment syndrome
child
drug reaction
title Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
title_full Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
title_fullStr Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
title_full_unstemmed Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
title_short Claudication Due to Sciatic Nerve Palsy Following Nicolau Syndrome: A Case Report
title_sort claudication due to sciatic nerve palsy following nicolau syndrome a case report
topic benzathine penicillin
compartment syndrome
child
drug reaction
url https://jcdr.net/articles/PDF/6596/14833_CE(RA1)_F(T)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf
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AT javaherkhajavikhan claudicationduetosciaticnervepalsyfollowingnicolausyndromeacasereport
AT moloukjaafarpour claudicationduetosciaticnervepalsyfollowingnicolausyndromeacasereport