THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS

It is believed that the concentration of C‑reactive protein (CRP) significantly increases in acute forms of systemic lupus erythematosus (SLE). A moderate increase of CRP levels in patients with stable disease progression reflects the low‑grade chronic inflammation in the vascular wall and the devel...

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Main Authors: S. M. Noskov, O. A. Vasilevskaja, T. S. Noskova, N. A. Arzimanova
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Klinicist
Subjects:
Online Access:https://klinitsist.abvpress.ru/Klin/article/view/63
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author S. M. Noskov
O. A. Vasilevskaja
T. S. Noskova
N. A. Arzimanova
author_facet S. M. Noskov
O. A. Vasilevskaja
T. S. Noskova
N. A. Arzimanova
author_sort S. M. Noskov
collection DOAJ
description It is believed that the concentration of C‑reactive protein (CRP) significantly increases in acute forms of systemic lupus erythematosus (SLE). A moderate increase of CRP levels in patients with stable disease progression reflects the low‑grade chronic inflammation in the vascular wall and the development of subclinical atherosclerosis. The article presents data showing that increased CRP levels in SLE patients is not statistically related with disease activity and cardiovascular risk as well as the level of interleykin‑6. Patients with lupus nephritis have lower CRP concentration compared to patients without renal disease and CRP concentration depends on proteinuria and hypoalbuminemia.
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spelling doaj.art-54f2c956e4644ea4b04f2e19beabdf6c2023-03-30T20:14:07ZrusABV-pressKlinicist1818-83382014-07-0161101410.17650/1818-8338-2012-1-10-1478THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUSS. M. Noskov0O. A. Vasilevskaja1T. S. Noskova2N. A. Arzimanova3Yaroslavl state medical academy, Ministry of Health and Social Development of RussiaYaroslavl state medical academy, Ministry of Health and Social Development of RussiaYaroslavl state medical academy, Ministry of Health and Social Development of RussiaYaroslavl state medical academy, Ministry of Health and Social Development of RussiaIt is believed that the concentration of C‑reactive protein (CRP) significantly increases in acute forms of systemic lupus erythematosus (SLE). A moderate increase of CRP levels in patients with stable disease progression reflects the low‑grade chronic inflammation in the vascular wall and the development of subclinical atherosclerosis. The article presents data showing that increased CRP levels in SLE patients is not statistically related with disease activity and cardiovascular risk as well as the level of interleykin‑6. Patients with lupus nephritis have lower CRP concentration compared to patients without renal disease and CRP concentration depends on proteinuria and hypoalbuminemia.https://klinitsist.abvpress.ru/Klin/article/view/63c‑reactive proteinsystemic lupus erythematosus
spellingShingle S. M. Noskov
O. A. Vasilevskaja
T. S. Noskova
N. A. Arzimanova
THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
Klinicist
c‑reactive protein
systemic lupus erythematosus
title THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
title_full THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
title_fullStr THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
title_full_unstemmed THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
title_short THE SIGNIFICANCE OF C‑REACTIVE PROTEIN IN SYSTEMIC LUPUS ERYTHEMATOSUS
title_sort significance of c reactive protein in systemic lupus erythematosus
topic c‑reactive protein
systemic lupus erythematosus
url https://klinitsist.abvpress.ru/Klin/article/view/63
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