Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ)
Abstract Background/Objectives Heavy menstrual bleeding (HMB) affects 34% to 37% of adolescent girls. The Menstrual Bleeding Questionnaire (MBQ) is a validated measure of menstrual bleeding–specific health‐related quality of life (HRQoL) for women aged ≥18 years. No similar measure existed for adole...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-10-01
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| Series: | Research and Practice in Thrombosis and Haemostasis |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rth2.12615 |
| _version_ | 1797726570158227456 |
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| author | Meghan Pike Ashley Chopek Nancy L. Young Koyo Usuba Mark J. Belletrutti Robyn McLaughlin Nancy Van Eyk Amanda Bouchard Kristen Matteson Victoria E. Price |
| author_facet | Meghan Pike Ashley Chopek Nancy L. Young Koyo Usuba Mark J. Belletrutti Robyn McLaughlin Nancy Van Eyk Amanda Bouchard Kristen Matteson Victoria E. Price |
| author_sort | Meghan Pike |
| collection | DOAJ |
| description | Abstract Background/Objectives Heavy menstrual bleeding (HMB) affects 34% to 37% of adolescent girls. The Menstrual Bleeding Questionnaire (MBQ) is a validated measure of menstrual bleeding–specific health‐related quality of life (HRQoL) for women aged ≥18 years. No similar measure existed for adolescents with HMB. Patients/Methods HMB was defined by the Pictorial Bleeding Assessment Chart (PBAC) score ≥100. In Phase 1, a focus group of adolescents with HMB adapted the MBQ, to generate the Adolescent MBQ (aMBQ). In phase 2, participants with and without HMB were recruited from clinics and self‐referral. Each participant completed 3 questionnaires (aMBQ, Pediatric Quality of Life module [PedsQL]©, PBAC) at two time points. Validity of the aMBQ was assessed by Pearson’s correlation with the PedsQL©. Reliability was calculated using intra‐class correlation (ICC) in those without HMB. The receiver operating characteristic curve assessed the aMBQ’s ability to identify those with HMB. Results Phase 1 included five girls with a mean age of 17.1 (13‐18) years. The aMBQ was adapted from the MBQ by substituting four words/phrases that altered 8 of the 20 questions and by adding 1 new question. The 21‐item aMBQ has a score range of 0 to 77 (77 = worst HRQoL). Phase 2 included 52 participants: 20 with and 32 without HMB, with a mean age of 14.8 (11‐17) years. The validity of the aMBQ was confirmed by a moderate correlation with PedsQL© (r = −0.63; P < .001). Test‐retest reliability was substantial (ICC = 0.73; P = .04). An aMBQ score of >30 identified those with HMB with excellent discrimination (area under the curve = 0.82; sensitivity, 70.0%; specificity, 84.4%). Conclusions The aMBQ is a valid and reliable tool to assess HRQoL in adolescents with HMB. |
| first_indexed | 2024-03-12T10:47:31Z |
| format | Article |
| id | doaj.art-54f32e0e324143c5a06bb5974bf71d6c |
| institution | Directory Open Access Journal |
| issn | 2475-0379 |
| language | English |
| last_indexed | 2024-03-12T10:47:31Z |
| publishDate | 2021-10-01 |
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| record_format | Article |
| series | Research and Practice in Thrombosis and Haemostasis |
| spelling | doaj.art-54f32e0e324143c5a06bb5974bf71d6c2023-09-02T07:21:35ZengElsevierResearch and Practice in Thrombosis and Haemostasis2475-03792021-10-0157n/an/a10.1002/rth2.12615Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ)Meghan Pike0Ashley Chopek1Nancy L. Young2Koyo Usuba3Mark J. Belletrutti4Robyn McLaughlin5Nancy Van Eyk6Amanda Bouchard7Kristen Matteson8Victoria E. Price9Division of Pediatric Hematology‐Oncology Department of Pediatrics Dalhousie UniversityIWK Health Centre Halifax Nova Scotia CanadaCancer Care Manitoba Winnipeg Manitoba CanadaChildren's Hospital of Eastern Ontario Research Institute Ottawa Ontario CanadaLaurentian University Sudbury Ontario CanadaDepartment of Pediatrics University of Alberta Edmonton Alberta CanadaDepartment of Pediatrics IWK Health Centre Halifax Nova Scotia CanadaDepartment of Obstetrics and Gynecology IWK Health Centre Halifax Nova Scotia CanadaDivision of Pediatric Hematology‐Oncology Department of Pediatrics Dalhousie UniversityIWK Health Centre Halifax Nova Scotia CanadaWomen and Infants Hospital and Warren Alpert Medical School of Brown University Providence Rhode Island USADivision of Pediatric Hematology‐Oncology Department of Pediatrics Dalhousie UniversityIWK Health Centre Halifax Nova Scotia CanadaAbstract Background/Objectives Heavy menstrual bleeding (HMB) affects 34% to 37% of adolescent girls. The Menstrual Bleeding Questionnaire (MBQ) is a validated measure of menstrual bleeding–specific health‐related quality of life (HRQoL) for women aged ≥18 years. No similar measure existed for adolescents with HMB. Patients/Methods HMB was defined by the Pictorial Bleeding Assessment Chart (PBAC) score ≥100. In Phase 1, a focus group of adolescents with HMB adapted the MBQ, to generate the Adolescent MBQ (aMBQ). In phase 2, participants with and without HMB were recruited from clinics and self‐referral. Each participant completed 3 questionnaires (aMBQ, Pediatric Quality of Life module [PedsQL]©, PBAC) at two time points. Validity of the aMBQ was assessed by Pearson’s correlation with the PedsQL©. Reliability was calculated using intra‐class correlation (ICC) in those without HMB. The receiver operating characteristic curve assessed the aMBQ’s ability to identify those with HMB. Results Phase 1 included five girls with a mean age of 17.1 (13‐18) years. The aMBQ was adapted from the MBQ by substituting four words/phrases that altered 8 of the 20 questions and by adding 1 new question. The 21‐item aMBQ has a score range of 0 to 77 (77 = worst HRQoL). Phase 2 included 52 participants: 20 with and 32 without HMB, with a mean age of 14.8 (11‐17) years. The validity of the aMBQ was confirmed by a moderate correlation with PedsQL© (r = −0.63; P < .001). Test‐retest reliability was substantial (ICC = 0.73; P = .04). An aMBQ score of >30 identified those with HMB with excellent discrimination (area under the curve = 0.82; sensitivity, 70.0%; specificity, 84.4%). Conclusions The aMBQ is a valid and reliable tool to assess HRQoL in adolescents with HMB.https://doi.org/10.1002/rth2.12615adolescentheavy menstrual bleedingmenorrhagiapatient‐reported outcome measuressurveys and questionnaires |
| spellingShingle | Meghan Pike Ashley Chopek Nancy L. Young Koyo Usuba Mark J. Belletrutti Robyn McLaughlin Nancy Van Eyk Amanda Bouchard Kristen Matteson Victoria E. Price Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) Research and Practice in Thrombosis and Haemostasis adolescent heavy menstrual bleeding menorrhagia patient‐reported outcome measures surveys and questionnaires |
| title | Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) |
| title_full | Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) |
| title_fullStr | Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) |
| title_full_unstemmed | Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) |
| title_short | Quality of life in adolescents with heavy menstrual bleeding: Validation of the Adolescent Menstrual Bleeding Questionnaire (aMBQ) |
| title_sort | quality of life in adolescents with heavy menstrual bleeding validation of the adolescent menstrual bleeding questionnaire ambq |
| topic | adolescent heavy menstrual bleeding menorrhagia patient‐reported outcome measures surveys and questionnaires |
| url | https://doi.org/10.1002/rth2.12615 |
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